ID   INSULIN; PATTERN.
AC   PS00262;
DT   01-APR-1990 CREATED; 01-DEC-2004 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
DE   Insulin family signature.
PA   C-C-{P}-{P}-x-C-[STDNEKPI]-x(3)-[LIVMFS]-x(3)-C.
NR   /RELEASE=2024_02,571282;
NR   /TOTAL=262(262); /POSITIVE=254(254); /UNKNOWN=0(0); /FALSE_POS=8(8);
NR   /FALSE_NEG=10; /PARTIAL=1;
CC   /TAXO-RANGE=??E??; /MAX-REPEAT=1;
CC   /SITE=1,disulfide; /SITE=2,disulfide; /SITE=6,disulfide;
CC   /SITE=11,disulfide;
CC   /VERSION=1;
DR   Q17192    , BXA1_BOMMO , T; P33718    , BXA1_SAMCY , T;
DR   P15411    , BXA2_BOMMO , T; P33719    , BXA2_SAMCY , T;
DR   P26726    , BXA3_BOMMO , T; P33720    , BXA3_SAMCY , T;
DR   P26727    , BXA4_BOMMO , T; P26728    , BXA5_BOMMO , T;
DR   P26729    , BXA6_BOMMO , T; P26730    , BXA7_BOMMO , T;
DR   P26731    , BXA8_BOMMO , T; P26732    , BXA9_BOMMO , T;
DR   Q17194    , BXB10_BOMMO, T; P29519    , BXB12_BOMMO, T;
DR   P26733    , BXB1_BOMMO , T; P33721    , BXB1_SAMCY , T;
DR   P26734    , BXB2_BOMMO , T; P33722    , BXB2_SAMCY , T;
DR   P26737    , BXB3_BOMMO , T; P26738    , BXB4_BOMMO , T;
DR   P26739    , BXB5_BOMMO , T; P26740    , BXB6_BOMMO , T;
DR   P26741    , BXB7_BOMMO , T; P26742    , BXB8_BOMMO , T;
DR   P26743    , BXB9_BOMMO , T; P15410    , BXC1_BOMMO , T;
DR   P26735    , BXC2_BOMMO , T; P26736    , BXD1_BOMMO , T;
DR   P21808    , BXE1_BOMMO , T; P91896    , BXF1_BOMMO , T;
DR   O61271    , BXG1_BOMMO , T; O09209    , BXRA_AGRCO , T;
DR   O09210    , BXRB_AGRCO , T; C9K4X8    , GSS_PATPE  , T;
DR   Q90325    , IGF1A_CYPCA, T; P16501    , IGF1A_XENLA, T;
DR   Q90326    , IGF1B_CYPCA, T; P84775    , IGF1B_XENLA, T;
DR   Q6IVA5    , IGF1_AILFU , T; Q6JLX1    , IGF1_AILME , T;
DR   P07455    , IGF1_BOVIN , T; P33712    , IGF1_CANLF , T;
DR   P51457    , IGF1_CAPHI , T; P17647    , IGF1_CAVPO , T;
DR   P18254    , IGF1_CHICK , T; P51462    , IGF1_COTJA , T;
DR   P51458    , IGF1_HORSE , T; P05019    , IGF1_HUMAN , T;
DR   P05017    , IGF1_MOUSE , T; P17085    , IGF1_ONCKI , T;
DR   Q02815    , IGF1_ONCMY , T; Q6GUL6    , IGF1_PANTA , T;
DR   P16545    , IGF1_PIG   , T; Q95222    , IGF1_RABIT , T;
DR   P08025    , IGF1_RAT   , T; Q68LC0    , IGF1_RHIRO , T;
DR   P10763    , IGF1_SHEEP , T; Q28933    , IGF1_SUNMU , T;
DR   Q90WW4    , IGF2A_XENLA, T; Q6INW9    , IGF2B_XENLA, T;
DR   P07456    , IGF2_BOVIN , T; Q08279    , IGF2_CAVPO , T;
DR   P33717    , IGF2_CHICK , T; P51459    , IGF2_HORSE , T;
DR   P01344    , IGF2_HUMAN , T; P09535    , IGF2_MOUSE , T;
DR   P41694    , IGF2_NEOVI , T; Q02816    , IGF2_ONCMY , T;
DR   P23695    , IGF2_PIG   , T; P01346    , IGF2_RAT   , T;
DR   P10764    , IGF2_SHEEP , T; Q90WX8    , IGF3_XENLA , T;
DR   P22618    , IGF_MYXGL  , T; Q09626    , ILB1_CAEEL , T;
DR   Q09627    , ILB2_CAEEL , T; Q09628    , ILB3_CAEEL , T;
DR   Q23430    , ILB4_CAEEL , T; P56174    , ILB5_CAEEL , T;
DR   P56173    , ILB6_CAEEL , T; Q18060    , ILG1_CAEEL , T;
DR   P22334    , ILP_BRACL  , T; G5EFH1    , INS17_CAEEL, T;
DR   A0A0B5AC95, INS1A_CONGE, T; A0A0B5ABE6, INS1A_CONQU, T;
DR   A0A0B5ADU4, INS1A_CONTU, T; A0A0B5A8Q2, INS1B_CONGE, T;
DR   A0A0B5ABE4, INS1B_CONQU, T; A0A0B5AC90, INS1B_CONTU, T;
DR   A0A0B5A7P2, INS1C_CONGE, T; P01337    , INS1_BATSP , T;
DR   A0A0B5AC98, INS1_CONFO , T; A0A0B5A7M7, INS1_CONIM , T;
DR   A0A3S9V8L7, INS1_CONKI , T; A0A0B5ADV0, INS1_CONME , T;
DR   A0A0B5A8Q6, INS1_CONMR , T; A0A0B5A7N8, INS1_CONTE , T;
DR   C0HJI7    , INS1_HUSDA , T; C0HJI2    , INS1_KATPE , T;
DR   P01325    , INS1_MOUSE , T; P01322    , INS1_RAT   , T;
DR   C0HJI5    , INS1_THUOR , T; P12706    , INS1_XENLA , T;
DR   A0A0B5ADT9, INS2A_CONFO, T; A0A0B5ABD9, INS2A_CONGE, T;
DR   A0A0B5A7N1, INS2B_CONFO, T; A0A0B5ADT3, INS2B_CONGE, T;
DR   A0A0B5A7N5, INS2C_CONFO, T; P01338    , INS2_BATSP , T;
DR   A0A0B5A8P8, INS2_CONIM , T; A0A3S9V8K6, INS2_CONKI , T;
DR   A0A3S9V8L9, INS2_CONTU , T; C0HJI8    , INS2_HUSDA , T;
DR   C0HJI3    , INS2_KATPE , T; P01326    , INS2_MOUSE , T;
DR   P01323    , INS2_RAT   , T; C0HJI6    , INS2_THUOR , T;
DR   P12707    , INS2_XENLA , T; A0A0B5A8P4, INS3A_CONGE, T;
DR   A0A0B5AC86, INS3B_CONGE, T; A0A0B5ABD5, INS3_CONTU , T;
DR   Q9VT50    , INSL1_DROME, T; Q9VT51    , INSL2_DROME, T;
DR   O77801    , INSL3_BOVIN, T; O97937    , INSL3_CALJA, T;
DR   Q6X7V3    , INSL3_CANLF, T; Q9VT52    , INSL3_DROME, T;
DR   P51460    , INSL3_HUMAN, T; O09107    , INSL3_MOUSE, T;
DR   Q5CZK3    , INSL3_PANTR, T; P51461    , INSL3_PIG  , T;
DR   Q9WUK0    , INSL3_RAT  , T; Q9VT53    , INSL4_DROME, T;
DR   Q14641    , INSL4_HUMAN, T; Q5CZK6    , INSL4_PANTR, T;
DR   Q7KUD5    , INSL5_DROME, T; Q9Y5Q6    , INSL5_HUMAN, T;
DR   Q9WUG6    , INSL5_MOUSE, T; Q5CZK5    , INSL5_PANTR, T;
DR   Q32L79    , INSL6_BOVIN, T; Q9Y581    , INSL6_HUMAN, T;
DR   Q9QY05    , INSL6_MOUSE, T; Q9WV41    , INSL6_RAT  , T;
DR   P81423    , INS_ACIGU  , T; P01324    , INS_ACOCA  , T;
DR   P12703    , INS_ALLMI  , T; P29335    , INS_AMICA  , T;
DR   P01333    , INS_ANAPL  , T; P41522    , INS_ANGAN  , T;
DR   P42633    , INS_ANGRO  , T; P68245    , INS_ANSAN  , T;
DR   P67972    , INS_AOTTR  , T; P09476    , INS_ATRSP  , T;
DR   P01314    , INS_BALBO  , T; P67973    , INS_BALPH  , T;
DR   P01317    , INS_BOVIN  , T; P68243    , INS_CAIMO  , T;
DR   P13190    , INS_CALMI  , T; P01320    , INS_CAMDR  , T;
DR   P01321    , INS_CANLF  , T; P01319    , INS_CAPHI  , T;
DR   C0HJI1    , INS_CARSE  , T; P01329    , INS_CAVPO  , T;
DR   P01327    , INS_CHICH  , T; P67970    , INS_CHICK  , T;
DR   P68991    , INS_CHIMO  , T; P30407    , INS_CHLAE  , T;
DR   A0A0F7YYV0, INS_CONVC  , T; P01313    , INS_CRILO  , T;
DR   P01334    , INS_CROAT  , T; P01335    , INS_CYPCA  , T;
DR   O73727    , INS_DANRE  , T; P18109    , INS_DIDVI  , T;
DR   P01316    , INS_ELEMA  , T; P06306    , INS_FELCA  , T;
DR   P01336    , INS_GADMC  , T; Q6YK33    , INS_GORGO  , T;
DR   P01310    , INS_HORSE  , T; P01308    , INS_HUMAN  , T;
DR   P68992    , INS_HYDCO  , T; P01328    , INS_HYSCR  , T;
DR   Q91XI3    , INS_ICTTR  , T; P01340    , INS_KATPE  , T;
DR   P68988    , INS_LAMFL  , T; P69045    , INS_LOPAM  , T;
DR   P69046    , INS_LOPPI  , T; P30406    , INS_MACFA  , T;
DR   P67968    , INS_MELGA  , T; P01330    , INS_MYOCO  , T;
DR   P07453    , INS_MYOSC  , T; P01342    , INS_MYXGL  , T;
DR   P17715    , INS_OCTDE  , T; P68989    , INS_ONCGO  , T;
DR   P04667    , INS_ONCKE  , T; P68990    , INS_ONCKI  , T;
DR   P81025    , INS_ORENI  , T; Q9TQY7    , INS_ORNAN  , T;
DR   C0HJI4    , INS_PAGMA  , T; Q98TA8    , INS_PANBU  , T;
DR   P30410    , INS_PANTR  , T; P68987    , INS_PETMA  , T;
DR   P67974    , INS_PHYMC  , T; P81881    , INS_PIAME  , T;
DR   P01315    , INS_PIG    , T; P09477    , INS_PLAFE  , T;
DR   C0HJU0    , INS_PLATA  , T; Q8HXV2    , INS_PONPY  , T;
DR   P01331    , INS_PROGU  , T; Q62587    , INS_PSAOB  , T;
DR   P12708    , INS_PTYDH  , T; P01311    , INS_RABIT  , T;
DR   P67971    , INS_SAISC  , T; P51463    , INS_SELRF  , T;
DR   C0HJT9    , INS_SERQU  , T; P01318    , INS_SHEEP  , T;
DR   P12704    , INS_SQUAC  , T; P67969    , INS_STRCA  , T;
DR   P01339    , INS_THUTH  , T; P12705    , INS_TORMA  , T;
DR   P69047    , INS_TRADO  , T; P69048    , INS_TRASC  , T;
DR   Q9W7R2    , INS_VERMO  , T; C0HKS3    , IRP1_AGRIP , T;
DR   C0HKS4    , IRP2_AGRIP , T; C0HKS5    , IRP4_AGRIP , T;
DR   P15131    , LIRP_LOCMI , T; P07223    , MPI1_LYMST , T;
DR   P25289    , MPI2_LYMST , T; P80090    , MPI3_LYMST , T;
DR   P31241    , MPI5_LYMST , T; P91797    , MPI7_LYMST , T;
DR   P04808    , REL1_HUMAN , T; P51454    , REL1_PANTR , T;
DR   P01347    , REL1_RAT   , T; P04090    , REL2_HUMAN , T;
DR   P51455    , REL2_PANTR , T; Q8WXF3    , REL3_HUMAN , T;
DR   Q8CHK2    , REL3_MOUSE , T; Q5CZK2    , REL3_PANTR , T;
DR   Q8HY17    , REL3_PIG   , T; Q8BFS3    , REL3_RAT   , T;
DR   P51456    , RELH_RABIT , T; P11184    , RELX_BALAC , T;
DR   P11185    , RELX_BALED , T; Q9TRM8    , RELX_CANLF , T;
DR   P01349    , RELX_CARTA , T; P51453    , RELX_CAVPO , T;
DR   Q9MYK8    , RELX_FELCA , T; P22969    , RELX_HORSE , T;
DR   P81191    , RELX_HYPSI , T; P11952    , RELX_LEUER , T;
DR   P19884    , RELX_MACMU , T; Q64171    , RELX_MESAU , T;
DR   P01348    , RELX_PIG   , T; P11953    , RELX_SQUAC , T;
DR   Q7M3C4    , RELX_PHODA , P;
DR   Q17196    , BXB11_BOMMO, N; Q21507    , ILA1_CAEEL , N;
DR   Q21508    , ILA2_CAEEL , N; Q21506    , ILA3_CAEEL , N;
DR   Q9W4Z4    , INSL6_DROME, N; Q9W4Q9    , INSL7_DROME, N;
DR   P83770    , INSL_VIGUN , N; P0C236    , INS_POLSE  , N;
DR   P21563    , INS_RODSP  , N; P47932    , REL1_MOUSE , N;
DR   Q95194    , ADA18_MACFA, F; Q5BK84    , ADAM5_RAT  , F;
DR   P85032    , F256_CTEON , F; Q6AWT8    , GG3_ARATH  , F;
DR   Q5K0C4    , O161_CONCE , F; Q3YEE6    , O165_CONLI , F;
DR   B0B9D1    , PRMC_CHLT2 , F; O84027    , PRMC_CHLTR , F;
3D   1A7F; 1AI0; 1AIY; 1APH; 1B17; 1B18; 1B19; 1B2A; 1B2B; 1B2C; 1B2D; 1B2E;
3D   1B2F; 1B2G; 1B9E; 1B9G; 1BEN; 1BOM; 1BON; 1BPH; 1BQT; 1BZV; 1CPH; 1DEI;
3D   1DPH; 1EFE; 1EV3; 1EV6; 1EVR; 1FU2; 1FUB; 1G7A; 1G7B; 1GUJ; 1GZR; 1GZY;
3D   1GZZ; 1H02; 1H59; 1HIQ; 1HIS; 1HIT; 1HLS; 1HTV; 1HUI; 1IGL; 1IMX; 1IOG;
3D   1IOH; 1IZA; 1IZB; 1J73; 1JCA; 1JCO; 1K3M; 1KMF; 1LKQ; 1LPH; 1M5A; 1MHI;
3D   1MHJ; 1MPJ; 1MSO; 1OS3; 1OS4; 1PID; 1PMX; 1Q4V; 1QIY; 1QIZ; 1QJ0; 1RWE;
3D   1SDB; 1SF1; 1SJT; 1SJU; 1T1K; 1T1P; 1T1Q; 1TGR; 1TRZ; 1TYL; 1TYM; 1UZ9;
3D   1W8P; 1WAV; 1WQJ; 1XDA; 1XGL; 1XW7; 1ZEG; 1ZEH; 1ZEI; 1ZNI; 1ZNJ; 2A3G;
3D   2AIY; 2BN1; 2BN3; 2C8Q; 2C8R; 2CEU; 2DSP; 2DSQ; 2DSR; 2EFA; 2FHW; 2G4M;
3D   2GF1; 2H67; 2H8B; 2HH4; 2HHO; 2HIU; 2INS; 2JMN; 2JUM; 2JUU; 2JUV; 2JV1;
3D   2JZQ; 2K1V; 2K6T; 2K6U; 2K91; 2K9R; 2KBC; 2KJI; 2KJJ; 2KJU; 2KQP; 2KQQ;
3D   2KXK; 2L1Y; 2L1Z; 2L29; 2LGB; 2LWZ; 2M1D; 2M1E; 2M2M; 2M2N; 2M2O; 2M2P;
3D   2MLI; 2MPG; 2MPI; 2MV1; 2MVC; 2MVD; 2N2V; 2N2W; 2N2X; 2OLY; 2OLZ; 2OM0;
3D   2OM1; 2OMG; 2OMH; 2OMI; 2QIU; 2R34; 2R35; 2R36; 2RN5; 2TCI; 2V5P; 2VJZ;
3D   2VK0; 2W44; 2WBY; 2WC0; 2WFU; 2WFV; 2WRU; 2WRV; 2WRW; 2WRX; 2WS0; 2WS1;
3D   2WS4; 2WS6; 2WS7; 2ZP6; 2ZPP; 3AIY; 3BXQ; 3E4Z; 3E7Y; 3E7Z; 3EXX; 3FHP;
3D   3FQ9; 3GF1; 3GKY; 3I3Z; 3I40; 3ILG; 3INC; 3INS; 3IR0; 3JSD; 3KQ6; 3KR3;
3D   3LRI; 3MTH; 3P2X; 3P33; 3Q6E; 3ROV; 3RTO; 3T2A; 3TT8; 3U4N; 3V19; 3V1G;
3D   3W11; 3W12; 3W13; 3W7Y; 3W7Z; 3W80; 3ZI3; 3ZQR; 3ZS2; 3ZU1; 4A7E; 4AIY;
3D   4AJX; 4AJZ; 4AK0; 4AKJ; 4BS3; 4CXL; 4CXN; 4CY7; 4E7T; 4E7U; 4E7V; 4EFX;
3D   4EWW; 4EWX; 4EWZ; 4EX0; 4EX1; 4EXX; 4EY1; 4EY9; 4EYD; 4EYN; 4EYP; 4F0N;
3D   4F0O; 4F1A; 4F1B; 4F1C; 4F1D; 4F1F; 4F1G; 4F4T; 4F4V; 4F51; 4F8F; 4FG3;
3D   4FKA; 4GBC; 4GBI; 4GBK; 4GBL; 4GBN; 4I5Y; 4I5Z; 4IDW; 4IHN; 4INS; 4IUZ;
3D   4IYD; 4IYF; 4M4F; 4M4H; 4M4I; 4M4J; 4M4L; 4M4M; 4NIB; 4OGA; 4P65; 4RXW;
3D   4UNE; 4UNG; 4UNH; 4XC4; 4XSS; 5AIY; 5BOQ; 5BPO; 5BQQ; 5BTS; 5CJO; 5CNY;
3D   5CO2; 5CO6; 5CO9; 5D52; 5D53; 5D54; 5D5E; 5E7W; 5EMS; 5EN9; 5ENA; 5FB6;
3D   5HPR; 5HPU; 5HQI; 5HRQ; 5JYQ; 5KQV; 5L3L; 5L3M; 5L3N; 5LIS; 5MAM; 5MHD;
3D   5MIZ; 5MT3; 5MT9; 5MWQ; 5U8Q; 5UDP; 5UOZ; 5UQA; 5URT; 5URU; 5USP; 5USS;
3D   5USV; 5UU2; 5UU3; 5UU4; 5VIZ; 5WBT; 5WDM; 5WOB; 6B3Q; 6B70; 6BFC; 6CE7;
3D   6CE9; 6CEB; 6CK2; 6FEY; 6FF3; 6GNQ; 6GV0; 6HN5; 6INS; 6JK8; 6JR3; 6K59;
3D   6KH8; 6KH9; 6KHA; 6NWV; 6O17; 6OR0; 6P4Z; 6PYH; 6Q8Q; 6QQ7; 6QQG; 6QRH;
3D   6QRK; 6RLX; 6RVA; 6S34; 6S4I; 6S4J; 6SOF; 6TC2; 6TYH; 6U46; 6UM2; 6VEP;
3D   6VEQ; 6VER; 6VES; 6VET; 6VWG; 6VWI; 6X4X; 6Z7W; 6Z7Y; 6Z7Z; 6ZHB; 6ZI8;
3D   7AC4; 7BW7; 7BW8; 7BWA; 7ELJ; 7INS; 7JP3; 7KD6; 7MD4; 7MD5; 7MQO; 7MQR;
3D   7MQS; 7NHU; 7PG0; 7PG2; 7PG3; 7PG4; 7QAC; 7QGF; 7QID; 7RKD; 7RZE; 7RZF;
3D   7RZI; 7S0Q; 7S4Y; 7SL1; 7SL2; 7SL3; 7SL4; 7SL6; 7SL7; 7STH; 7STI; 7STJ;
3D   7STK; 7U6E; 7V3P; 7WRQ; 7YJ4; 7YQ3; 7YQ4; 7YQ5; 7YRR; 7Z5L; 7Z5Q; 8EYR;
3D   8EYX; 8EYY; 8EZ0; 8GSG; 8GUY; 8PI4; 8PI5; 8PI6; 8PJC; 8PJH; 8SBD; 9INS;
DO   PDOC00235;
//