ID   HAMP; MATRIX.
AC   PS50885;
DT   01-DEC-2002 CREATED; 10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
DE   HAMP domain profile.
MA   /GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=52;
MA   /DISJOINT: DEFINITION=PROTECT; N1=1; N2=52;
MA   /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=5.2466869; R2=0.0000936; TEXT='NScore';
MA   /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=242215.5000000; R2=0.7340519; PRIORITY=1; TEXT='Heuristic 5.0%';
MA   /CUT_OFF: LEVEL=0; SCORE=18732; H_SCORE=255966; N_SCORE=7.0; MODE=1; TEXT='!';
MA   /CUT_OFF: LEVEL=-1; SCORE=13391; H_SCORE=252045; N_SCORE=6.5; MODE=1; TEXT='?';
MA   /DEFAULT: B0=*; B1=*; E0=*; E1=*; MM=*; II=*;
MA   /I: B0=-8455; B1=-8455; BM=-2; BD=-9306;
MA   /M: SY='R'; M=-259,-3211,-1293,-1046,-1925,-135,553,-2425,652,-1183,-981,382,-4678,-269,2917,-770,-412,-2742,949,-754; M0=-862;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='R'; M=-62,-7878,-780,-1091,-456,-621,143,-926,-659,-624,-593,633,-1216,511,1847,690,396,-998,1603,-115; M0=-363;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='I'; M=-813,-6593,-3402,-3384,-366,-514,-1670,2361,-2966,1324,791,-3320,-8275,245,-1605,-1182,-580,1018,-1955,-1623; M0=-1314;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='T'; M=196,-3466,-1552,-1387,-824,-1844,-2355,581,-1176,938,394,-562,-5454,117,-731,376,1493,1051,-1281,-4386; M0=-668;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='R'; M=416,-7890,-1100,-805,-1581,-355,219,-3180,1329,-1757,-897,140,-4893,645,2512,-461,89,-1454,-2126,-3537; M0=-926;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='P'; M=103,-2444,-2498,-3044,-4615,-1449,-2451,-2530,-1961,-4713,-6962,-1854,3615,407,746,-1068,-2170,-1314,-2910,-1631; M0=-1794;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='L'; M=-1523,-2413,-9075,-5119,-1584,-8277,-7148,2202,-8034,2283,350,-7923,-8327,-7657,-7834,-3117,-1936,1455,-1987,-3498; M0=-3742;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='R'; M=-174,-7891,369,416,-3803,-775,146,-1108,606,-831,-2845,974,-4105,685,2075,-137,11,-1303,-395,-1854; M0=-660;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='R'; M=519,-7892,258,1076,-4577,-720,323,-2364,542,-1812,-1254,-121,-4738,1372,1943,-293,-27,-1526,-8075,-1959; M0=-914;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='L'; M=-839,-2434,-5785,-8437,-464,-8275,-3746,1598,-8032,2515,1764,-7921,-8325,-2582,-5964,-3962,-1400,498,-7011,-1597; M0=-3377;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='T'; M=1159,-7888,-1889,-402,-8207,-300,-976,-401,-15,-787,-519,-174,-7487,169,775,741,1159,690,-8072,-3178; M0=-1026;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='E'; M=521,-3412,898,1274,-8213,-599,416,-2774,531,-1983,-2000,445,-4738,1113,1254,-120,84,-890,-2086,-3436; M0=-919;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='A'; M=1901,-1905,-1841,-627,-2197,507,258,-1225,-850,-1192,-736,-2077,-6388,612,-228,-32,329,1093,-8019,-1008; M0=-765;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='M'; M=1931,-1834,-9075,-8439,-594,-4768,-7148,720,-8034,915,2576,-7923,-8327,-7657,-7834,-585,852,816,-3825,-6671; M0=-3384;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='Q'; M=269,-3369,738,1279,-8213,-761,446,-2049,861,-1695,-1258,275,-4144,1368,1345,-330,123,-1723,-8075,-2922; M0=-939;
MA   /I: MM=-2; MI=-14472; MD=-9291; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='R'; M=1369,-7890,240,528,-3145,-2459,806,-3986,882,-2594,-1676,-133,-3519,940,2167,-295,-877,-2689,-8073,-2248; M0=-1171;
MA   /I: MM=0; MI=-14470; MD=-15512; IM=-894; II=-1115; DM=-1449; DD=-658;
MA   /M: SY='I'; M=-950,-2692,-9071,-8435,98,-3816,-7144,2392,-5003,1425,1630,-4926,-4766,-7652,-864,-3579,-2295,1777,-1411,-2073; M0=-2707;
MA   /I: MM=0; MI=-14470; MD=-15512; IM=-894; II=-1115; DM=-1449; DD=-658;
MA   /M: SY='A'; M=2626,-7889,-983,-465,-8210,273,-1883,-2062,-1800,-4324,-1161,-2599,-4631,-400,227,1246,-320,-2802,-8073,-4220; M0=-1730;
MA   /I: MM=-173; MI=-3184; MD=-8366; IM=-1273; II=-770; DM=-1449; DD=-658;
MA   /M: SY='D'; M=1018,-3993,1222,913,-4570,-709,311,-3568,369,-2143,-2273,777,-685,884,884,635,-1124,-3046,-8069,-3574; M0=-883;
MA   /I: MM=0; MI=-14466; MD=-15508; IM=-894; II=-1115; DM=-200; DD=-2952;
MA   /M: SY='G'; M=-1829,-1808,-1008,-1753,-3275,3436,-685,-7960,-1916,-1921,-4017,-347,-2629,-713,-710,-2360,-2936,-3920,-8074,-2804; M0=-2087;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='D'; M=-1651,-2478,3310,360,-8213,-2692,-104,-5582,-822,-4413,-3889,1697,-3446,-162,-4,-1569,-1615,-2578,-8075,-3325; M0=-2044;
MA   /I: MM=-115; MI=-14472; MD=-3704; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='L'; M=-3741,-6534,-3067,-2809,1858,-3707,-2091,-1198,-2668,2647,-581,-2937,-1144,-2976,-1345,-2299,-1345,-2222,-802,1246; M0=-1689;
MA   /I: MM=0; MI=-14357; MD=-15399; IM=-894; II=-1115; DM=-63; DD=-4540;
MA   /M: SY='T'; M=-107,-7888,1566,-185,-4461,-749,-427,-3097,-626,-1631,-4547,247,-1279,-650,-217,1379,2049,-2290,-8071,-4918; M0=-1067;
MA   /I: MM=-74; MI=-4322; MD=-15511; IM=-170; II=-3171; DM=-1759; DD=-505;
MA   /M: SY='Q'; M=692,-2268,-2095,166,-1648,-2011,992,-442,208,-1485,-2152,-1220,-746,1363,623,-218,539,1288,-2198,-73; M0=-408;
MA   /I: MM=0; MI=-14469; MD=-15511; IM=-894; II=-1115; DM=-295; DD=-2436;
MA   /M: SY='R'; M=-1019,-5446,198,-185,-3493,-3539,-96,-1736,350,-1764,-2351,-1641,1264,310,2969,-632,-426,-2255,-8074,-3202; M0=-1124;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='I'; M=-270,-1201,-3270,-2620,-535,-4098,-3653,2247,-8031,1642,434,-3742,-1343,-7654,-2784,-2987,-1677,1743,-7011,-1516; M0=-1971;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='P'; M=-251,-2339,1310,1283,-3196,-1820,-665,-2895,-29,-4584,-3151,189,2294,-168,-352,-204,447,-1568,-8075,-2076; M0=-1010;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='V'; M=-52,-2860,-197,727,-1228,-293,-226,854,-1624,-268,-511,-1362,-57,-402,-1283,-744,203,1769,-1906,-1048; M0=-308;
MA   /I: MM=-5191; MI=-40; MD=-15514; IM=0; II=-12173; DM=-701; DD=-1378;
MA   /M: SY='G'; M=-339,-2212,-132,-726,793,1886,-357,-2168,-1180,-2448,-2645,-321,-990,-1655,1101,908,558,-1310,-8068,-631; M0=-630;
MA   /I: MM=-554; MI=-1649; MD=-15514; IM=-699; II=-1381; DM=-701; DD=-1378;
MA   /M: SY='P'; M=-301,-1949,470,-85,-3635,72,228,-915,869,-2871,-2917,917,1356,645,1254,-123,-346,-1071,-2910,-2454; M0=-527;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='D'; M=-643,-3455,3318,-652,-3144,513,-1905,-3732,-2830,-2413,-4241,63,-124,-651,-574,-728,-1212,-2412,-8073,-1616; M0=-1307;
MA   /I: MM=-6; MI=-14472; MD=-7878; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='E'; M=-1523,-2451,-543,3768,-5019,-3770,-6057,-4464,-5643,-5579,-6949,-3870,-3547,-1945,-2377,-1957,-3275,-2568,-8048,-7374; M0=-3207;
MA   /I: MM=-2; MI=-14466; MD=-9225; IM=-894; II=-1115; DM=-211; DD=-2877;
MA   /M: SY='I'; M=-2733,-6561,-9081,-8445,1657,-8283,-2892,2459,-8040,1640,1270,-7929,-3655,-7662,-7839,-7368,-1244,1028,-2902,-7; M0=-3876;
MA   /I: MM=0; MI=-14470; MD=-15512; IM=-894; II=-1115; DM=-1474; DD=-644;
MA   /M: SY='G'; M=767,-3048,232,112,-3444,2660,-1038,-3621,-1724,-1708,-6976,-1142,-5130,-220,649,-623,-749,-2139,-2059,-2293; M0=-1197;
MA   /I: MM=0; MI=-14470; MD=-15512; IM=-894; II=-1115; DM=-1474; DD=-644;
MA   /M: SY='Q'; M=224,-3435,870,1292,-3142,-2032,-205,-1090,-147,-1112,-312,-552,-176,1984,1258,-749,-634,-1057,-3088,-2062; M0=-521;
MA   /I: MM=0; MI=-14470; MD=-15512; IM=-894; II=-1115; DM=-368; DD=-2152;
MA   /M: SY='L'; M=-1097,-7076,-9662,-9043,-2594,-8909,-7804,992,-8659,2784,1720,-8557,-8911,-8256,-5220,-3902,-2113,683,-7597,-7284; M0=-4450;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='A'; M=2344,-1508,-6987,-1923,-2162,718,-3703,-471,-524,-2185,-357,-1140,-4983,-1127,252,517,89,247,-7489,-2157; M0=-1167;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='R'; M=448,-2394,823,619,-2128,-910,772,-1410,459,-1776,-1603,353,-3903,1164,1843,-820,-84,-475,-8074,-2790; M0=-633;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='A'; M=2026,-3500,769,-883,-2794,-227,-385,-2596,-2880,-3078,-6971,364,-7489,-555,-1796,1559,930,-1513,-3462,-1480; M0=-1322;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='F'; M=-4319,-6558,-9078,-8442,3545,-8280,-3713,1359,-8037,1193,279,-5052,-8330,-7660,-7837,-4400,-2609,594,-7016,-843; M0=-4135;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='N'; M=-1175,-3938,168,129,-4743,-2277,-1673,-2174,-1820,-3095,-3043,3891,-7487,-698,-327,-2499,-2316,-3124,-8072,-3183; M0=-2077;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='Q'; M=672,-7889,601,681,-2938,-808,823,-1396,-98,-1564,-766,8,-7487,1381,1104,269,502,-347,-3058,-1543; M0=-733;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='M'; M=79,-3235,-9073,-8437,1557,-8275,-3849,-2043,-8032,566,4521,-3853,-8325,-7655,-7832,-989,-516,-1943,-7011,-1989; M0=-3764;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='A'; M=1222,-1967,-5188,-8257,-1962,-2137,-878,551,-825,893,830,-3494,-8298,946,1191,-275,-350,1066,-7029,-1919; M0=-1486;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='D'; M=642,-7891,1877,1821,-3086,-262,-49,-2940,-493,-2535,-1311,-942,-7486,1077,-238,-171,84,-1336,-8075,-2883; M0=-1150;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='R'; M=89,-7892,-1187,457,-3706,-1008,295,-3585,745,-3849,-2098,1564,-7486,1171,1926,910,41,-2594,-8075,-2780; M0=-1388;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='L'; M=-1055,-6554,-9073,-2621,-1368,-3571,-7146,1334,-8032,2762,-255,-2102,-8325,-2645,-7831,-3818,-1749,443,-3330,-2316; M0=-2926;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='Q'; M=-46,-2535,-530,1443,-3574,-1145,848,-1063,417,-1109,-3112,-200,-7487,1777,1640,264,-1124,-1111,-1948,-2510; M0=-846;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='E'; M=617,-3328,943,1429,-2421,-127,438,-1856,248,-1970,-1785,-57,-3307,1252,727,-42,361,-2109,-8075,-2329; M0=-658;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='M'; M=566,-7486,-2619,-2029,-168,-2236,-190,122,-507,796,1348,-1178,-7628,443,503,515,1060,-103,-1007,-12; M0=-740;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='I'; M=-584,-3634,-1207,-236,391,-4182,-1267,1840,-2111,636,1544,-1318,-5573,186,158,-1876,-665,1251,-2058,255; M0=-836;
MA   /I: MM=0; MI=-14472; MD=-15514; IM=-894; II=-1115; DM=-701; DD=-1378;
MA   /M: SY='E'; M=818,-1623,571,1453,-3480,-84,-165,-1767,73,-1267,-3193,85,-7486,973,1198,184,-513,-1343,-8074,-1760; M0=-811;
MA   /I: E0=-1000; E1=-1000;
CC   /MATRIX_TYPE=protein_domain;
CC   /SCALING_DB=reversed;
CC   /AUTHOR=CJA_Sigrist;
CC   /FT_KEY=DOMAIN; /FT_DESC=HAMP;
CC   /VERSION=6;
PR   PRU00102;
DO   PDOC50885;
//