ID   SHKT; MATRIX.
AC   PS51670;
DT   01-MAR-2013 CREATED; 01-MAR-2013 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
DE   ShKT domain profile.
MA   /GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=35;
MA   /DISJOINT: DEFINITION=PROTECT; N1=1; N2=35;
MA   /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.4714091; R2=0.0058477; TEXT='NScore';
MA   /CUT_OFF: LEVEL=0; SCORE=689; N_SCORE=7.5; MODE=1; TEXT='R';
MA   /CUT_OFF: LEVEL=-1; SCORE=518; N_SCORE=6.5; MODE=1; TEXT='RR';
MA   /DEFAULT: M0=-50; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
MA   /I: B1=0; BI=-255; BD=-255;
MA   /M: SY='C'; M=-91,158,-111,-111,-101,-107,-111,-108,-107,-99,-99,-97,-122,-115,-113,-94,-91,-96,-131,-112;
MA   /M: SY='K'; M=-14,-26,0,36,-45,-72,-34,-24,36,8,-32,-40,-17,7,24,2,35,-45,-106,-20;
MA   /I: I=-28; MD=-71;
MA   /M: SY='H'; M=-117,-129,20,-35,-67,-122,80,-29,-59,-96,-108,-2,-123,-25,-23,-50,-112,-23,-120,51; D=-28;
MA   /I: I=-28; MD=-71;
MA   /M: SY='E'; M=-111,-127,-91,68,-123,-120,-47,-125,-23,-125,-119,30,-61,-60,-105,-18,-19,-45,-128,4; D=-28;
MA   /I: I=-28; MI=-71; IM=-71; DM=-71;
MA   /M: SY='D'; M=-54,-105,104,-70,-27,-90,-80,-57,-83,-72,-105,84,-100,-84,-92,-82,-84,-107,-126,-98;
MA   /M: SY='K'; M=-25,-106,16,9,-99,-101,-6,-52,57,8,-29,-52,20,19,28,-25,7,-11,-7,-48;
MA   /I: I=-26; MD=-65;
MA   /M: SY='F'; M=-1,-105,-57,-101,78,-51,33,-11,-24,-21,-85,9,-110,-97,-18,-15,-35,-71,-84,69; D=-26;
MA   /I: I=-26; MD=-65;
MA   /M: SY='T'; M=-30,-100,-29,-53,-4,-66,-16,-2,-8,-72,-18,12,-17,-91,-95,44,76,-14,-113,-48; D=-26;
MA   /I: I=-26; MI=-65; MD=-65; IM=-65; DM=-65;
MA   /M: SY='N'; M=-47,14,26,-15,-62,-90,-10,-10,-38,-69,-34,98,-103,-40,-30,8,-26,-31,34,-29; D=-26;
MA   /I: I=-26; DM=-65;
MA   /M: SY='C'; M=-91,158,-111,-111,-101,-107,-111,-108,-107,-99,-99,-97,-122,-115,-113,-94,-91,-96,-131,-112;
MA   /M: SY='P'; M=1,-109,29,-2,-111,4,-94,-106,34,-81,-102,32,49,-35,-29,-8,14,-44,17,-103;
MA   /M: SY='D'; M=2,-106,47,-45,-18,-52,29,-19,-29,-43,-11,-11,-36,-6,-8,43,5,-25,-16,3;
MA   /M: SY='W'; M=-65,-110,-114,-62,0,-112,-104,-27,-32,58,22,-9,-113,-50,-103,-66,-61,-36,119,14;
MA   /M: SY='A'; M=46,-102,-99,-24,-101,-99,-101,-10,33,-38,-89,-93,-102,-16,13,-6,19,37,-112,-99;
MA   /I: I=-15; MD=-39;
MA   /M: SY='K'; M=-9,-112,-32,-25,-59,-28,-12,-108,50,-41,-100,-2,-52,41,21,19,-12,-48,-114,-42; D=-15;
MA   /I: I=-15; MD=-39;
MA   /M: SY='Q'; M=-55,-113,-65,-11,-20,-52,-38,-32,5,-17,-20,14,-107,75,20,5,3,-64,-111,-24; D=-15;
MA   /I: I=-15; MD=-39;
MA   /M: SY='G'; M=-37,-120,-23,-110,-64,48,-65,-75,-56,-40,-111,23,-117,-14,-33,13,-53,-14,-125,-60; D=-15;
MA   /I: I=-15; MD=-39;
MA   /M: SY='M'; M=-78,-121,-57,1,13,19,-13,-111,-5,-9,20,4,-118,-47,-108,10,-41,-112,-15,-29; D=-15;
MA   /I: I=-15; MI=0; MD=-39; IM=0; DM=-39;
MA   /M: SY='C'; M=-99,150,-119,-119,-109,-114,-119,-116,-115,-107,-107,-105,-130,-122,-121,-101,-99,-103,-139,-120;
MA   /M: SY='Q'; M=-97,-115,-18,12,-58,-15,20,-69,26,-80,-57,36,-104,74,21,-18,-13,-111,-116,-100;
MA   /I: I=-20; MI=0; MD=-50; IM=0; DM=-50;
MA   /M: SY='H'; M=-69,-114,48,-47,-52,-108,51,-102,-10,-77,38,-38,13,-52,-45,11,26,-6,-125,-29; D=-20;
MA   /I: I=-20; DM=-50;
MA   /M: SY='E'; M=-88,-118,14,41,-63,-49,-97,-115,37,-82,-108,21,22,17,-19,12,-68,-45,-121,-109; D=-20;
MA   /I: I=-20; DM=-50;
MA   /M: SY='W'; M=-72,-117,-107,-100,18,-50,30,-97,-7,2,-91,-46,-113,39,-31,-44,-14,-68,98,72;
MA   /I: I=-22; MI=0; MD=-57; IM=0; DM=-57;
MA   /M: SY='M'; M=-66,-109,-75,-109,-42,-116,-99,26,-40,5,109,-108,-52,-99,-4,-106,-47,15,-109,1;
MA   /M: SY='K'; M=-6,-111,-47,-54,-37,-105,-34,-35,59,-33,-12,5,-57,28,26,-16,12,-73,-111,-19;
MA   /M: SY='S'; M=6,-32,-36,29,-55,-100,-33,-62,13,-47,-34,-5,-102,0,-8,47,26,-37,-117,-103;
MA   /M: SY='N'; M=-79,-110,-1,-65,22,-55,-16,-49,18,-9,-97,78,-110,1,-20,-3,-92,-104,-1,11;
MA   /M: SY='C'; M=-99,150,-119,-119,-109,-114,-119,-116,-115,-107,-107,-105,-130,-122,-121,-101,-99,-103,-139,-120;
MA   /M: SY='P'; M=26,-116,-101,-60,-118,-38,-101,-112,33,-66,-40,-98,71,22,30,-12,-96,-108,-115,-109;
MA   /M: SY='A'; M=61,-107,-101,-56,-36,-99,-103,-40,58,-51,-99,-55,-106,-90,4,-13,-68,-63,-113,-104;
MA   /M: SY='T'; M=-36,-102,-97,-98,-56,-98,-103,-58,-97,-106,-102,-86,-101,-95,-103,68,86,-95,-123,-104;
MA   /M: SY='C'; M=-100,149,-120,-120,-110,-116,-120,-117,-116,-108,-108,-106,-131,-124,-122,-103,-100,-105,-140,-121;
MA   /I: I=-24; MD=-61;
MA   /M: SY='G'; M=-115,-134,-21,-63,-17,49,-40,-140,-19,-137,-128,32,-128,-28,-26,-109,-119,-137,-134,-124; D=-24;
MA   /I: I=-24; MI=0; MD=-61; IM=0; DM=-61;
MA   /M: SY='F'; M=-70,-111,-61,-104,68,-65,-37,-58,20,20,-5,-57,-115,-1,-23,-15,7,-62,-13,-34;
MA   /M: SY='C'; M=-102,147,-122,-122,-112,-118,-122,-119,-118,-110,-110,-108,-133,-126,-124,-105,-102,-107,-142,-123;
MA   /I: E1=0; IE=-255; DE=-255;
NR   /RELEASE=2024_02,571282;
NR   /TOTAL=136(120); /POSITIVE=136(120); /UNKNOWN=0(0); /FALSE_POS=0(0);
NR   /FALSE_NEG=10; /PARTIAL=2;
CC   /MATRIX_TYPE=protein_domain;
CC   /SCALING_DB=reversed;
CC   /AUTHOR=CJA_Sigrist;
CC   /TAXO-RANGE=??E??; /MAX-REPEAT=4;
CC   /FT_KEY=DOMAIN; /FT_DESC=ShKT;
CC   /VERSION=1;
DR   O16846    , 1AK_HETMG  , T; Q0MWV8    , AURE_AURAU , T;
DR   P54107    , CRIS1_HUMAN, T; Q9XSD3    , CRIS1_MACMU, T;
DR   Q03401    , CRIS1_MOUSE, T; P12020    , CRIS1_RAT  , T;
DR   Q60477    , CRIS2_CAVPO, T; P16562    , CRIS2_HUMAN, T;
DR   P16563    , CRIS2_MOUSE, T; O19010    , CRIS3_HORSE, T;
DR   P54108    , CRIS3_HUMAN, T; Q03402    , CRIS3_MOUSE, T;
DR   P0CB15    , CRIS_PROFL , T; Q2XXQ6    , CRVP1_DISTY, T;
DR   Q8UW25    , CRVP1_HYDHA, T; Q7T1K6    , CRVP1_NAJAT, T;
DR   P84805    , CRVP1_NAJKA, T; Q2XXQ3    , CRVP1_PSEPL, T;
DR   Q2XXQ5    , CRVP2_DISTY, T; Q8UW11    , CRVP2_HYDHA, T;
DR   Q7ZZN8    , CRVP2_NAJAT, T; P84808    , CRVP2_NAJKA, T;
DR   Q2XXQ2    , CRVP2_PSEPL, T; Q2XXQ4    , CRVP3_DISTY, T;
DR   Q2XXR0    , CRVP5_VARAC, T; Q2XXP2    , CRVPA_VARVA, T;
DR   Q2XXP1    , CRVPB_VARVA, T; Q7ZTA0    , CRVP_AGKPI , T;
DR   A8S6B6    , CRVP_AUSSU , T; A7X4T8    , CRVP_CAURH , T;
DR   D8VNS1    , CRVP_CERRY , T; F8S0Y4    , CRVP_CROAD , T;
DR   Q7ZT99    , CRVP_CROAT , T; A6MFK9    , CRVP_DEMVE , T;
DR   F8J2D4    , CRVP_DRYCN , T; P0DMT4    , CRVP_ECHCO , T;
DR   Q2XXQ0    , CRVP_ERYPO , T; Q8JI40    , CRVP_GLOBL , T;
DR   Q91055    , CRVP_HELHO , T; Q3SB03    , CRVP_HOPST , T;
DR   Q8JI38    , CRVP_LATSE , T; Q2XXQ1    , CRVP_LEIMD , T;
DR   Q3SB04    , CRVP_NOTSC , T; Q7ZT98    , CRVP_OPHHA , T;
DR   Q3SB06    , CRVP_OXYMI , T; Q3SB07    , CRVP_OXYSC , T;
DR   Q09GJ9    , CRVP_PHIOL , T; Q8JI39    , CRVP_PROFL , T;
DR   Q7ZZN9    , CRVP_PROJR , T; P79845    , CRVP_PROMU , T;
DR   Q8AVA4    , CRVP_PSEAU , T; Q8AVA3    , CRVP_PSEPO , T;
DR   Q3SB05    , CRVP_PSETE , T; Q8JGT9    , CRVP_RHATT , T;
DR   B0VXV6    , CRVP_SISCA , T; Q2XXP5    , CRVP_TELDH , T;
DR   Q2XXP4    , CRVP_TRIBI , T; P60623    , CRVP_TRIST , T;
DR   B7FDI1    , CRVP_VIPBE , T; B7FDI0    , CRVP_VIPBN , T;
DR   P0DUB0    , CUE3_CONIM , T; Q0EAE5    , K1A_ANEER  , T;
DR   E2S064    , K1A_CRYAD  , T; E2S065    , K1A_HETHE  , T;
DR   E2S061    , K1A_STIGI  , T; E2S062    , K1A_STIHA  , T;
DR   P29187    , K1A_STIHL  , T; E2S063    , K1A_STIME  , T;
DR   E2S066    , K1A_THAAS  , T; C0HJC2    , K1B1_BUNCI , T;
DR   A0A330KW27, K1B1_OULSP , T; C0HJC3    , K1B2_BUNCI , T;
DR   A0A330KUG5, K1B2_OULSP , T; P0DN00    , K1B9A_ANEVI, T;
DR   P0DN02    , K1B9C_ANEVI, T; P0DN03    , K1B9D_ANEVI, T;
DR   P0DN04    , K1BAA_ANEVI, T; P0DN05    , K1BBA_ANEVI, T;
DR   P81897    , K1B_ACTEQ  , T; Q9TWG1    , K1B_ANESU  , T;
DR   P29186    , K1B_BUNGR  , T; P11495    , K1B_METSE  , T;
DR   Q95Q39    , MAB7_CAEEL , T; P27424    , MFAP2_BOVIN, T;
DR   P55001    , MFAP2_HUMAN, T; P55002    , MFAP2_MOUSE, T;
DR   Q23490    , MLT7_CAEEL , T; Q2TBM7    , MMP23_BOVIN, T;
DR   O75900    , MMP23_HUMAN, T; O88676    , MMP23_MOUSE, T;
DR   O88272    , MMP23_RAT  , T; Q21388    , NAS10_CAEEL, T;
DR   Q21432    , NAS11_CAEEL, T; Q9XTD6    , NAS12_CAEEL, T;
DR   Q20191    , NAS13_CAEEL, T; Q19269    , NAS14_CAEEL, T;
DR   P55115    , NAS15_CAEEL, T; Q7JLI1    , NAS31_CAEEL, T;
DR   O16977    , NAS32_CAEEL, T; Q9U3S9    , NAS6_CAEEL , T;
DR   P55113    , NAS7_CAEEL , T; Q18439    , NAS8_CAEEL , T;
DR   D2KBH9    , NAS8_STECR , T; P91137    , NAS9_CAEEL , T;
DR   A7RNZ0    , NEP4_NEMVE , T; A7SXG9    , NEP8_NEMVE , T;
DR   Q8GXT7    , P4H12_ARATH, T; F4JAU3    , P4H2_ARATH , T;
DR   Q8LAN3    , P4H4_ARATH , T; Q8L970    , P4H7_ARATH , T;
DR   Q20616    , SKPO1_CAEEL, T; H3JU05    , SRGT1_CHLRE, T;
DR   Q9XU75    , SURO1_CAEEL, T; P54190    , TES26_TOXCA, T;
DR   P34269    , TYR1_CAEEL , T; Q19673    , TYR3_CAEEL , T;
DR   Q09337    , YOFA_CAEEL , T; P30652    , YOW6_CAEEL , T;
DR   Q09244    , YP95_CAEEL , T; Q09662    , YS51_CAEEL , T;
DR   P0DMG5    , CRVP_BOTCO , P; P0DMG6    , CRVP_BOTFO , P;
DR   P0DQR8    , CL8L_NEMVE , N; P0DN01    , K1B9B_ANEVI, N;
DR   P0DPF1    , K1HH_ANESU , N; A7RJ13    , NEP3L_NEMVE, N;
DR   A7RJ12    , NEP3_NEMVE , N; F4J0A8    , P4H6_ARATH , N;
DR   P0DQR6    , SHKL1_NEMVE, N; A7SRR3    , SHKL2_NEMVE, N;
DR   A7ST80    , SHKL4_NEMVE, N; P0DMZ7    , TX8E_ANEVI , N;
3D   1BEI; 1BGK; 1RC9; 1ROO; 1WVR; 1XTA; 1XX5; 2A05; 2CQ7; 2DDA; 2DDB; 2EPF;
3D   2GIZ; 2K72; 2K9E; 2LG4; 3MZ8; 4LFQ; 4LFS; 4Z7P; 5I5A; 5I5B; 5I5C; 5WCV;
3D   6BUC; 6CKD; 6CKF; 6IMF; 7OD2;
PR   PRU01005;
DO   PDOC51670;
//