AC   PRU00408;
DC   Domain;
TR   PROSITE; PS50879; RNASE_H_1; 1; level=0
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Names: Ribonuclease H type-1 domain
Function: Ribonuclease H (RNase H) (EC 3.1.26.4) recognizes and cleaves the
 RNA strand of RNA-DNA heteroduplexes.
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DE   + RecName: EC=3.1.26.4;
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CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage to 5'-phosphomonoester.; EC=3.1.26.4;
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GO   GO:0004519; F:endonuclease activity
GO   GO:0016787; F:hydrolase activity
GO   GO:0004518; F:nuclease activity
case <FTGroup:1>
GO   GO:0000287; F:magnesium ion binding
end case
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KW   Endonuclease
KW   Hydrolase
KW   Nuclease
case <FTGroup:1>
KW   Magnesium
KW   Metal-binding
end case
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FT   From: PS50879
FT   DOMAIN          from..to
FT                   /note="RNase H type-1"
case not <OC:Bacteria> and not <OC:Archaea>
FT   BINDING         10
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: D
FT   BINDING         10
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="#2"
FT   Group: 1; Condition: D
FT   BINDING         50
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: E
FT   BINDING         72
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: D
FT   BINDING         136
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="#2"
FT   Group: 1; Condition: D
end case
XX
Chop: Nter=0; Cter=0;
Size: 101-205;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q08885;
Scope:
 Eukaryota
 Bacteria
 Archaea
 Viruses
Comments: None
XX
# Revision 1.19 2022/11/19
//