AC PRU00525; DC Domain; TR PROSITE; PS50258; LNR; 1-3; level=0 XX Names: Lin-12/Notch (LNR) repeat Function: The LNR is supposed to negatively regulates the Lin-12/Notch proteins activity, and participates in maintaining the receptor in its resting conformation prior to ligand binding. XX XX DR PROSITE; PS50258; LNR; 1-3; trigger=no XX GO GO:0005509; F:calcium ion binding GO GO:0007219; P:Notch signaling pathway XX case KW Calcium KW Metal-binding end case case KW Disulfide bond end case XX FT From: PS50258 FT REPEAT entry..exit FT /note="LNR #" FT DISULFID 1..25 FT Tag: disulf; Condition: C-x*-C FT DISULFID 7..20 FT Tag: disulf; Condition: C-x*-C FT DISULFID 16..32 FT Tag: disulf; Condition: C-x*-C FT BINDING 13 FT /ligand="Ca(2+)" FT /ligand_id="ChEBI:CHEBI:29108" FT Group: 1; Condition: [DN] FT BINDING 28 FT /ligand="Ca(2+)" FT /ligand_id="ChEBI:CHEBI:29108" FT Group: 1; Condition: D FT BINDING 31 FT /ligand="Ca(2+)" FT /ligand_id="ChEBI:CHEBI:29108" FT Group: 1; Condition: [DE] XX Chop: Nter=0; Cter=0; Size: 35-45; Related: none; Repeats: 1-3; Topology: Undefined; Example: Q3T906; Scope: Eukaryota Comments: None XX # Revision 1.10 2022/11/19 //