AC   PRU00607;
DC   Domain;
TR   PROSITE; PS51275; PEPTIDASE_C26_GGH; 1; level=0
XX
Names: Gamma-glutamyl hydrolase domain
 Peptidase C26 family. GGH subfamily.
Function: Gamma-glutamyl hydrolase (GGH) (EC 3.4.19.9) is an enzyme that
 cleaves gamma-linked glutamyl bonds, and with particular substrate the enzyme
 acts as an endopeptidase.
XX
case <FTGroup:1>
DE   + RecName: EC=3.4.19.9;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O =
CC         (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate;
CC         Xref=Rhea:RHEA:56784, Rhea:RHEA-COMP:14738, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:29985, ChEBI:CHEBI:57453, ChEBI:CHEBI:141005;
CC         EC=3.4.19.9;
XX
GO   GO:0034722; F:gamma-glutamyl-peptidase activity
GO   GO:0016787; F:hydrolase activity
XX
KW   Hydrolase
end case
XX
FT   From: PS51275
FT   DOMAIN          from..to
FT                   /note="Gamma-glutamyl hydrolase #"
FT   ACT_SITE        110
FT                   /note="Nucleophile"
FT   Group: 1; Condition: C
FT   ACT_SITE        222
FT   Group: 1; Condition: H
XX
Chop: Nter=0; Cter=0;
Size: 280-310;
Related: PRU00605;
Repeats: 1;
Topology: Undefined;
Example: Q92820;
Scope:
 Eukaryota
Comments: None
XX
# Revision 1.12 2021/10/28
//