AC PRU00652; DC Domain; TR PROSITE; PS51322; UEV; 1; level=0 XX Names: UEV domain Function: The N-terminal ubiquitin E2 variant (UEV) domain is ~145 amino acid residues in length and shows significant sequence similarity to E2 ubiquitin ligases but is unable to catalyze ubiquitin transfer as it lacks the active site cysteine that forms the transient thioester bond with the C-terminus of ubiquitin (Ub). Nevertheless, at least some UEVs have retained the ability to bind Ub, and appear to act either as cofactors in ubiquitylation reactions, or as ubiquitin sensors. XX XX FT From: PS51322 FT DOMAIN from..to FT /note="UEV #" XX Chop: Nter=0; Cter=0; Size: 134-160; Related: None; Repeats: 1; Topology: Undefined; Example: Q9LHG8; Scope: Eukaryota Comments: None; XX # Revision 1.3 2019/11/21 //