AC   PRU00674;
DC   Domain;
TR   PROSITE; PS51342; COLIPASE_2; 1; level=0
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Names: Colipase family
Function: Colipase is a small protein of ~100 amino acids that functions as a
 cofactor for pancreatic lipase. It also binds to the bile-salt covered
 triacylglycerol interface thus allowing the enzyme to anchor itself to the
 water-lipid interface. Colipases contain ten cysteines involved in five
 disulfide bonds.
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case <FTGroup:1>
CC   -!- FUNCTION: Colipase is a cofactor of pancreatic lipase. It allows the
CC       lipase to anchor itself to the lipid-water interface. Without colipase
CC       the enzyme is washed off by bile salts, which have an inhibitory effect
CC       on the lipase.
CC   -!- SUBUNIT: Forms a 1:1 stoichiometric complex with pancreatic lipase.
CC   -!- SUBCELLULAR LOCATION: Secreted.
end case
CC   -!- SIMILARITY: Belongs to the colipase family.
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case <FTGroup:1>
DR   PROSITE; PS00121; COLIPASE_1; 1; trigger=no
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GO   GO:0007586; P:digestion
GO   GO:0016042; P:lipid catabolic process
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KW   Digestion
KW   Lipid degradation
KW   Lipid metabolism
KW   Secreted
end case
case <FTTag:disulf>
KW   Disulfide bond
end case
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FT   From: PS51342
FT   DISULFID        12..23
FT   Tag: disulf; Group: 1; Condition: C-x*-C
FT   DISULFID        18..34
FT   Tag: disulf; Group: 1; Condition: C-x*-C
FT   DISULFID        22..56
FT   Tag: disulf; Group: 1; Condition: C-x*-C
FT   DISULFID        44..64
FT   Tag: disulf; Group: 1; Condition: C-x*-C
FT   DISULFID        58..82
FT   Tag: disulf; Group: 1; Condition: C-x*-C
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Chop: Nter=0; Cter=0;
Size: 80-90;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q91XL7;
Scope:
 Eukaryota; Metazoa; Vertebrata
Comments: None
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# Revision 1.7 2019/11/21
//