AC   PRU00677;
DC   Domain;
TR   PROSITE; PS51345; MYOTOXINS_2; 1; level=0
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Names: Myotoxins family
Function: Myotoxins are small basic peptides (42 to 45 residues) from the
 venom of rattlesnakes that cause severe muscle necrosis by a non-enzymatic
 mechanism. Myotoxins contain six cysteines involved in three disulfide bonds.
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case <Feature:PS00459>
CC   -!- FUNCTION: This toxin specifically modifies voltage-sensitive sodium
CC       channels, it exhibits analgesic activity and causes severe muscle
CC       necrosis by a non-enzymatic mechanism. Moreover, it actively interacts
CC       with lipid membranes.
CC   -!- SUBCELLULAR LOCATION: Secreted.
end case
CC   -!- SIMILARITY: Belongs to the snake toxin myotoxin family.
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DR   PROSITE; PS00459; MYOTOXINS_1; 0-1; trigger=no
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case <Feature:PS00459>
GO   GO:0019870; F:potassium channel inhibitor activity
GO   GO:0008200; F:ion channel inhibitor activity
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KW   Secreted
KW   Ion channel impairing toxin
KW   Potassium channel impairing toxin
KW   Voltage-gated potassium channel impairing toxin
KW   Myotoxin
KW   Toxin
end case
case <FTTag:disulf>
KW   Disulfide bond
end case
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FT   From: PS51345
FT   DISULFID        4..36
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        11..30
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        18..37
FT   Tag: disulf; Condition: C-x*-C
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Chop: Nter=0; Cter=0;
Size: 35-50;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: O73799;
Scope:
 Eukaryota; Metazoa; Squamata; Serpentes
Comments: None
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# Revision 1.7 2021/06/03
//