AC   PRU00726;
DC   Domain;
TR   PROSITE; PS51393; LIPOXYGENASE_3; 1; level=0
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Names: Lipoxygenase iron-binding catalytic domain
Function: Lipoxygenases (EC 1.13.11.-) form a class of iron-containing fatty
 acid dioxygenases, which catalyze the hydroperoxidation of lipids, containing
 a cis,cis-1,4-pentadiene structure.
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case <OC:Viridiplantae>
DE   AltName: Full=lipoxygenase;
DE            EC=1.13.11.-;
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CC   -!- FUNCTION: Plant lipoxygenases may be involved in a number of diverse
CC       aspects of plant physiology including growth and development, pest
CC       resistance, and senescence or responses to wounding. Catalyzes the
CC       hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene
CC       structure.
end case
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case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC       Note=Binds 1 Fe cation per subunit.;
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end case
case <OC:Viridiplantae>
CC   -!- PATHWAY: Lipid metabolism; oxylipin biosynthesis.
end case
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case <OC:Metazoa>
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
end case
case <OC:Bacteria>
CC   -!- SUBCELLULAR LOCATION: Periplasm.
end case
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case <Feature:PS51393:340=H> and <Feature:PS51393:345=H>
DR   PROSITE; PS00711; LIPOXYGENASE_1; 1; trigger=no
end case
case <Feature:PS51393:530=H>
DR   PROSITE; PS00081; LIPOXYGENASE_2; 1; trigger=no
end case
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GO   GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
case <FTGroup:1>
GO   GO:0005506; F:iron ion binding
GO   GO:0046872; F:metal ion binding
end case
GO   GO:0016491; F:oxidoreductase activity
case <OC:Viridiplantae>
GO   GO:0006633; P:fatty acid biosynthetic process
GO   GO:0008610; P:lipid biosynthetic process
GO   GO:0031408; P:oxylipin biosynthetic process
end case
case <OC:Bacteria>
GO   GO:0042597; C:periplasmic space
end case
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KW   Dioxygenase
case <FTGroup:1>
KW   Iron
KW   Metal-binding
end case
KW   Oxidoreductase
case <OC:Viridiplantae>
KW   Lipid metabolism
KW   Lipid biosynthesis
KW   Fatty acid biosynthesis
KW   Fatty acid metabolism
KW   Oxylipin biosynthesis
end case
case <OC:Bacteria>
KW   Periplasm
end case
XX
FT   From: PS51393
FT   DOMAIN          from..to
FT                   /note="Lipoxygenase #"
FT   BINDING         340
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: H
FT   BINDING         345
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: H
FT   BINDING         530
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: H
FT   BINDING         534
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: [NH]
FT   BINDING         678
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: I
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Chop: Nter=1; Cter=0;
Size: 540-730;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q84YK8; Q9BYJ1; Q8RNT4;
Scope:
 Eukaryota
 Bacteria
Comments: None
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# Revision 1.12 2022/11/19
//