AC   PRU00774;
DC   Domain;
TR   PROSITE; PS51444; FH2; 1; level=0
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Names: Formin homology-2 (FH2) domain
Function: The defining feature of formins is a highly conserved ~400 residue
 region, the Formin Homology-2 (FH2) domain, which forms a head-to-tail ring-
 shaped dimer, and directly binds to the actin filament at its barbed end. The
 FH2 domain catalyzes the nucleation and elongation of actin filament,
 preventing capping proteins from binding to the barbed end.
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GO   GO:0003779; F:actin binding
GO   GO:0030036; P:actin cytoskeleton organization
GO   GO:0005856; C:cytoskeleton
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KW   Actin-binding
KW   Cytoskeleton
FT   From: PS51444
FT   DOMAIN          from..to
FT                   /note="FH2 #"
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Chop: Nter=0; Cter=0;
Size: 285-486;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: O60610;
Scope:
 Eukaryota
Comments: None;
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# Revision 1.3 2019/11/21
//