AC   PRU00780;
DC   Domain;
TR   PROSITE; PS51449; MTTASE_N; 1; level=0
TR   PROSITE; PS01278; MTTASE_RADICAL; 1; level=0
XX
Names: Methylthiotransferase domains
Function: Methylthiotransferases (MTTases) catalyze a C-H to C-S bond
 conversion in the methylthiolation of tRNA or ribosomal protein substrate.
XX
case <OC:Bacteria> or <OC:Archaea>
DE   + RecName: EC=2.-.-.-;
end case
XX
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC       Note=Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine.;
case <OC:Bacteria>
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
end case
XX
GO   GO:0005506; F:iron ion binding
GO   GO:0051539; F:4 iron, 4 sulfur cluster binding
case <OC:Bacteria> or <OC:Archaea>
GO   GO:0016740; F:transferase activity
end case
case <OC:Bacteria>
GO   GO:0005737; C:cytoplasm
end case
XX
KW   4Fe-4S
KW   Iron
KW   Iron-sulfur
KW   Metal-binding
KW   S-adenosyl-L-methionine
case <OC:Bacteria> or <OC:Archaea>
KW   Transferase
end case
case <OC:Bacteria>
KW   Cytoplasm
end case
XX
FT   From: PS51449
FT   DOMAIN          from..to
FT                   /note="MTTase N-terminal #"
FT   BINDING         10
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT   Condition: C
FT   BINDING         46
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT   Condition: C
FT   BINDING         77
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT   Condition: C
FT   From: PS01278
FT   BINDING         4
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT   BINDING         5
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT   BINDING         8
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
XX
Chop: Nter=0; Cter=0;
Size: 90-150;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q54KV4; B4RNW8;
Scope:
 Bacteria
 Eukaryota
 Archaea
Comments: None;
XX
# Revision 1.11 2022/11/19
//