AC   PRU00796;
DC   Protein;
TR   PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 1; level=0
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Names: Glucose-6-phosphate isomerase family
Function: Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) or phosphoglucose
 isomerase (PGI) is a glycolytic enzyme that catalyzes the reversible
 isomerization of glucose-6-phosphate and fructose-6-phosphate.
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ID   G6PI
DE   + RecName: Full=Glucose-6-phosphate isomerase;
DE            Short=GPI;
DE            EC=5.3.1.9;
DE   AltName: Full=Phosphoglucose isomerase;
DE            Short=PGI;
DE   AltName: Full=Phosphohexose isomerase;
DE            Short=PHI;
GN   Name=pgi;
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CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC         Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC         EC=5.3.1.9;
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 2/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the GPI family.
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DR   PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; 1; trigger=no
case <Feature:PS51463:472=K>
DR   PROSITE; PS00174; P_GLUCOSE_ISOMERASE_2; 1; trigger=no
end case
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GO   GO:0004347; F:glucose-6-phosphate isomerase activity
GO   GO:0006096; P:glycolytic process
GO   GO:0006094; P:gluconeogenesis
GO   GO:0005737; C:cytoplasm
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KW   Gluconeogenesis
KW   Glycolysis
KW   Isomerase
KW   Cytoplasm
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FT   From: PS51463
FT   ACT_SITE        328
FT                   /note="Proton donor"
FT   Condition: E
FT   ACT_SITE        360
FT   Condition: H
FT   ACT_SITE        472
FT   Condition: K
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Chop: Nter=0; Cter=0;
Size: 150-600;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q39SU1;
Scope:
 Bacteria
 Eukaryota
 Archaea
Comments: None;
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# Revision 1.6 2021/11/11
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