AC   PRU00855;
DC   Domain;
TR   PROSITE; PS51522; ZF_NANOS; 1; level=0
XX
Names: Zinc finger nanos-type
Function: The nanos-type zinc finger has two conserved Cys-Cys-His-Cys (CCHC)-
 type zinc-finger motifs that are indispensable for nanos function.
XX
case <Feature:PS51522:2=C> and <Feature:PS51522:5=C> and <Feature:PS51522:18=H> and <Feature:PS51522:29=C> and <Feature:PS51522:37=C> and <Feature:PS51522:40=C> and <Feature:PS51522:48=H> and <Feature:PS51522:53=C>
CC   -!- DOMAIN: The Nanos-type zinc finger is composed of two C2HC motifs, each
CC       motif binding one molecule of zinc. It is essential for the translation
CC       repression activity of the protein.
end case
CC   -!- SIMILARITY: Belongs to the nanos family.
XX
GO   GO:0006417; P:regulation of translation
GO   GO:0003723; F:RNA binding
case (<Feature:PS51522:2=CH> and <Feature:PS51522:5=CH> and <Feature:PS51522:18=HC> and <Feature:PS51522:29=CH>) or (<Feature:PS51522:37=CH> and <Feature:PS51522:40=CH> and <Feature:PS51522:48=HC> and <Feature:PS51522:53=CH>)
GO   GO:0008270; F:zinc ion binding
XX
KW   Metal-binding
KW   Zinc
end case
KW   RNA-binding
KW   Translation regulation
KW   Zinc-finger
XX
FT   From: PS51522
case (<Feature:PS51522:2=C> and <Feature:PS51522:5=C> and <Feature:PS51522:18=H> and <Feature:PS51522:29=C>) and (<Feature:PS51522:37=C> and <Feature:PS51522:40=C> and <Feature:PS51522:48=H> and <Feature:PS51522:53=C>)
FT   ZN_FING         from..to
FT                   /note="Nanos-type #"
else case (<Feature:PS51522:2=[CH]> and <Feature:PS51522:5=[CH]> and <Feature:PS51522:18=[HC]> and <Feature:PS51522:29=[CH]>) and (<Feature:PS51522:37=[CH]> and <Feature:PS51522:40=[CH]> and <Feature:PS51522:48=[HC]> and <Feature:PS51522:53=[CH]>)
FT   ZN_FING         from..to
FT                   /note="Nanos-type #; atypical"
else
FT   ZN_FING         from..to
FT                   /note="Nanos-type #; degenerate"
end case
case <FTGroup:1>
FT   MOTIF           2..29
FT                   /note="C2HC #1"
end case
case <FTGroup:2>
FT   MOTIF           37..53
FT                   /note="C2HC #2"
end case
FT   BINDING         2
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         5
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         18
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         29
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         37
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 2; Condition: [CH]
FT   BINDING         40
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 2; Condition: [CH]
FT   BINDING         48
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 2; Condition: [CH]
FT   BINDING         53
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 2; Condition: [CH]
XX
Chop: Nter=0; Cter=0;
Size: 45-65;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P60323;
Scope:
 Eukaryota; Metazoa
Comments: None;
XX
# Revision 1.9 2022/11/19
//