AC PRU00867; DC Domain; TR PROSITE; PS51534; SEFIR; 1; level=0 XX Names: SEFIR domain Function: The SEFIR domain (after SEFs and IL17Rs) is a conserved sequence segment identified in transmembrane receptors (including SEFs, IL17Rs) and soluble factors (including CIKS/ACT1) in eukaryotes and bacteria. It is related to the TIR domain. The similarity between the SEFIR and TIR domains involves the conserved boxes 1 and 2 of the TIR domain that are implicated in homotypic dimerization, but there is no sequence similarity between SEFIR domains and the TIR sequence box 3. XX XX FT From: PS51534 FT DOMAIN from..to FT /note="SEFIR #" XX Chop: Nter=0; Cter=0; Size: 127-175; Related: None; Repeats: 1; Topology: Undefined; Example: Q8QHJ9; Scope: Eukaryota; Metazoa Comments: None; XX # Revision 1.3 2019/11/21 //