AC PRU00896; DC Domain; c? =464> and TR PROSITE; PS51563; SAM_MTA70L_1; 1; level=0 XX Names: N6-adenosine-methyltransferase catalytic subunit (EC=2.1.1.348) N6-adenosine-methyltransferase 70 kDa subunit (MT-A70) Function: The N6-methyltransferase complex methylates adenosine residues at the N(6) position of some RNAs. XX DE + RecName: EC=2.1.1.348; XX CC -!- CATALYTIC ACTIVITY: CC Reaction=an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)- CC methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine; CC Xref=Rhea:RHEA:55584, Rhea:RHEA-COMP:12414, Rhea:RHEA-COMP:12417, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, CC ChEBI:CHEBI:74411, ChEBI:CHEBI:74449; EC=2.1.1.348; CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase CC superfamily. MT-A70-like family. XX GO GO:0003723; F:RNA binding GO GO:0016422; F:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity GO GO:0001734; F:mRNA (N6-adenosine)-methyltransferase activity GO GO:0032259; P:methylation GO GO:0001510; P:RNA methylation XX KW Methyltransferase KW RNA-binding KW S-adenosyl-L-methionine KW Transferase XX Chop: Nter=0; Cter=0; Size: unlimited; Related: None; Repeats: 1; Topology: Undefined; Example: F1R777; Scope: Eukaryota Comments: None; XX # Revision 1.11 2022/01/03 //