AC PRU00898; DC Domain; TR PROSITE; PS51565; SAM_MT85_SETD3; 1; level=0 XX Names: SETD3 actin-histidine N-methyltransferase (EC 2.1.1.85) Function: SETD3 Actin-histidine N-methyltransferase (EC 2.1.1.85) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to L-histidine-[actin] to form N(tele)-methyl-L-histidine-[actin] and S-adenosyl-L-homocysteine. XX DE + RecName: EC=2.1.1.85; XX CC -!- CATALYTIC ACTIVITY: CC Reaction=L-histidyl-[protein] + S-adenosyl-L-methionine = H(+) + CC N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine; CC Xref=Rhea:RHEA:19369, Rhea:RHEA-COMP:9745, Rhea:RHEA-COMP:11600, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16367, ChEBI:CHEBI:29979, CC ChEBI:CHEBI:57856, ChEBI:CHEBI:59789; EC=2.1.1.85; CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19370; CC -!- SIMILARITY: Belongs to the class V-like SAM-binding methyltransferase CC superfamily. SETD3 actin-histidine methyltransferase family. XX GO GO:0018021; P:peptidyl-histidine methylation GO GO:0030047; P:actin modification XX KW Methyltransferase KW S-adenosyl-L-methionine KW Transferase XX Chop: Nter=0; Cter=0; Size: unlimited; Related: None; Repeats: 1; Topology: Undefined; Example: Q86TU7; Scope: Eukaryota Comments: None; XX # Revision 1.14 2019/11/21 //