AC   PRU00901;
DC   Domain;
TR   PROSITE; PS51568; SAM_MT43_SET2_1; 1; level=0
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Names: Histone-lysine N-methyltransferase (EC 2.1.1.43)
Function: Histone-lysine N-methyltransferase (EC 2.1.1.43) is an enzyme that
 transfers a methyl group from S-adenosyl-L-methionine (SAM) to L-lysine-
 [histone] to form N(6)-methyl-L-lysine-[histone] and S-adenosyl-L-
 homocysteine.
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DE   + RecName: EC=2.1.1.-;
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CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-
CC         methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:10024, Rhea:RHEA-COMP:9845, Rhea:RHEA-COMP:9846,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:61929;
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding methyltransferase
CC       superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
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GO   GO:0046975; F:histone H3K36 methyltransferase activity
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KW   Methyltransferase
KW   S-adenosyl-L-methionine
KW   Transferase
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Chop: Nter=0; Cter=0;
Size: unlimited;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q757Y8;
Scope:
 Eukaryota
Comments: None;
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# Revision 1.11 2022/09/30
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