AC PRU00956; DC Domain; c? =1280> and TR PROSITE; PS51624; SAM_MT_TRMH_2; 1; level=0 XX Names: RNA methyltransferase TRMH Function: tRNA guanosine-2'-O-methyltransferase (EC 2.1.1.34) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to tRNA to form tRNA containing 2'-O-methylguanosine and S-adenosyl-L-homocysteine. 16S rRNA (guanine(527)-N(7))-methyltransferase (EC 2.1.1.170) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to guanosine(527) in 16S rRNA to form N(7)-methylguanosine(527) in 16S rRNA and S-adenosyl-L-homocysteine. tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase (EC 2.1.1.200) is an enzyme that transfers a methyl group from S-adenosyl-L methionine (SAM) to (1)cytidine(32) in tRNA to form 2'-O-methylcytidine(32) in tRNA and S- adenosyl-L-homocysteine. tRNA (cytidine(34)-2'-O)-methyltransferase (EC 2.1.1.207) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to (1)cytidine(34) in tRNA to form 2'-O-methylcytidine(34) in tRNA and S adenosyl-L-homocysteine. XX DE + RecName: EC=2.1.1.-; XX CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase CC superfamily. RNA methyltransferase TrmH family. XX GO GO:0003723; F:RNA binding GO GO:0008173; F:RNA methyltransferase activity GO GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity GO GO:0006396; P:RNA processing GO GO:0032259; P:methylation GO GO:0046500; P:S-adenosylmethionine metabolic process XX KW Methyltransferase KW RNA-binding KW S-adenosyl-L-methionine KW Transferase XX FT From: PS51624 FT BINDING 1545 FT /ligand="S-adenosyl-L-methionine" FT /ligand_id="ChEBI:CHEBI:59789" FT Condition: G FT BINDING 1565 FT /ligand="S-adenosyl-L-methionine" FT /ligand_id="ChEBI:CHEBI:59789" FT Condition: I FT BINDING 1574 FT /ligand="S-adenosyl-L-methionine" FT /ligand_id="ChEBI:CHEBI:59789" FT Condition: L XX Chop: Nter=0; Cter=0; Size: unlimited; Related: None; Repeats: 1; Topology: Undefined; Example: Q13395; Scope: Eukaryota; Homo Comments: None; XX # Revision 1.8 2022/11/19 //