AC   PRU00958;
DC   Domain;
TR   PROSITE; PS51626; SAM_MT_TRM1; 1; level=0
XX
Names: tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216)
Function: tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) is an
 enzyme that transfers a methyl group from 2 S-adenosyl-L-methionine (SAM) to
 guanine(26) in tRNA to form N(2)-dimethylguanine(26) in tRNA and 2 S-
 adenosyl-L-homocysteine.
XX
case <OC:Eukaryota> and <Length>=425> and <Length<=670>
DE   + RecName: EC=2.1.1.216;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = 2 H(+) +
CC         N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:43140, Rhea:RHEA-COMP:10359, Rhea:RHEA-COMP:10360,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:74269, ChEBI:CHEBI:74513; EC=2.1.1.216;
end case
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. Trm1 family.
XX
case <OC:Eukaryota> and <Length>=425> and <Length<=670>
GO   GO:0160104; F:tRNA (guanine(26)-N2)-dimethyltransferase activity
end case
GO   GO:0000049; F:tRNA binding
GO   GO:0008033; P:tRNA processing
GO   GO:0032259; P:methylation
XX
KW   Methyltransferase
KW   RNA-binding
KW   S-adenosyl-L-methionine
KW   Transferase
KW   tRNA processing
KW   tRNA-binding
FT   From: PS51626
FT   DOMAIN          from..to
FT                   /note="Trm1 methyltransferase #"
XX
Chop: Nter=0; Cter=0;
Size: 58-472;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q9LFU5;
Scope:
 Archaea
 Eukaryota
 Bacteria; Aquifex
Comments: None;
XX
# Revision 1.15 2023/12/14
//