AC   PRU01018;
DC   Domain;
TR   PROSITE; PS51681; SAM_MT_NNMT_PNMT_TEMT; 1; level=0
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Names: NNMT, PNMT, TEMT and homologues.
Function: Function: Nicotinamide N-methyltransferase (EC 2.1.1.1) is an enzyme that
 transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide
 to form 1-methylnicotinamide and S-adenosyl-L-homocysteine.
 Phenylethanolamine N-methyltransferase (EC 2.1.1.28) is an enzyme that
 transfers a methyl group from S-adenosyl-L-methionine (SAM) to
 phenylethanolamine to form N-methylphenylethanolamine and S-adenosyl-L
 homocysteine.
 Amine N-methyltransferase (EC 2.1.1.49) is an enzyme that transfers a methyl
 group from S-adenosyl-L-methionine (SAM) to an amine to form a methylated
 amine and S-adenosyl-L-homocysteine.
 Thioether S-methyltransferase (EC 2.1.1.96) is an enzyme that transfers a
 methyl group from S-adenosyl-L-methionine (SAM) to dimethyl sulfide to form
 trimethylsulfonium and S-adenosyl-L-homocysteine.
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DE   + RecName: EC=2.1.1.-;
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CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. NNMT/PNMT/TEMT family.
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GO   GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity
GO   GO:0032259; P:methylation
GO   GO:0046500; P:S-adenosylmethionine metabolic process
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KW   Methyltransferase
KW   S-adenosyl-L-methionine
KW   Transferase
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FT   From: PS51681
FT   BINDING         13
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: Y
FT   BINDING         18
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: Y
FT   BINDING         55..56
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: G-[SA]
FT   BINDING         61
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: Y
FT   BINDING         77
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: D
FT   BINDING         82
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: N
FT   BINDING         134..135
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: [DN]-[VA]
FT   BINDING         155
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: [TFLAV]
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Chop: Nter=0; Cter=0;
Size: 251-260;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P40261;
Scope:
 Eukaryota; Metazoa
Comments: None;
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# Revision 1.2 2024/08/08
//