AC   PRU01031;
DC   Domain;
TR   PROSITE; PS51694; PEPTIDASE_M66; 1; level=0
XX
Names: Peptidase family M66 domain
Function: The peptidase family M66 domain is a zinc metalloprotease.
XX
case <FTGroup:1>
DE   + RecName: EC=3.4.24.-;
end case
XX
case <FTGroup:2>
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion per subunit.;
end case
XX
case <FTGroup:2>
GO   GO:0046872; F:metal ion binding
end case
case <FTGroup:1>
GO   GO:0006508; P:proteolysis
GO   GO:0004222; F:metalloendopeptidase activity
end case
XX
case <FTGroup:1>
KW   Hydrolase
KW   Metalloprotease
KW   Protease
end case
case <FTGroup:2>
KW   Metal-binding
KW   Zinc
end case
XX
FT   From: PS51694
FT   DOMAIN          from..to
FT                   /note="Peptidase M66"
FT   ACT_SITE        154
FT   Group: 1; Condition: E
FT   BINDING         153
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Group: 2; Condition: H
FT   BINDING         157
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Group: 2; Condition: H
FT   BINDING         163
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Group: 2; Condition: H
XX
Chop: Nter=0; Cter=0;
Size: 245-282;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: O82882;
Scope:
 Bacteria; Pseudomonadota
 Eukaryota; Dictyostelium
Comments: None;
XX
# Revision 1.8 2023/01/26
//