AC PRU01080; DC Domain; TR PROSITE; PS51744; HC_PRO_CPD; 1; level=0 XX Names: Helper-component proteinase (HC-Pro) cysteine protease (CPD) domain Peptidase C6 domain Function: The HC-Pro CPD domain has a protease activity that autocatalytically cleaves a Gly-Gly dipeptide at its own C terminus to release HC-Pro from the rest of the viral polyprotein. XX case and DE Contains: DE RecName: Full=Helper component proteinase; DE Short=HC-pro; DE EC=3.4.22.45; XX CC -!- FUNCTION: Helper component proteinase: Cysteine protease that cleaves a CC Gly-Gly dipeptide at its own C-terminus. CC -!- CATALYTIC ACTIVITY: CC Reaction=Hydrolyzes a Gly-|-Gly bond at its own C-terminus, commonly in CC the sequence -Tyr-Xaa-Val-Gly-|-Gly, in the processing of the CC potyviral polyprotein.; EC=3.4.22.45; end case XX case and GO GO:0004197; F:cysteine-type endopeptidase activity XX KW Hydrolase KW Protease end case XX FT From: PS51744 FT DOMAIN from..to FT /note="Peptidase C6 #" FT ACT_SITE 9 FT /note="For helper component proteinase activity" FT Group: 1; Condition: C FT ACT_SITE 81 FT /note="For helper component proteinase activity" FT Group: 1; Condition: H case FT SITE 122..122+1 FT /note="Cleavage; by autolysis" FT Group: 2 end case XX Chop: Nter=0; Cter=0; Size: 110-133; Related: None; Repeats: 1; Topology: Undefined; Example: P0CJ95; Scope: Viruses; Potyviridae Comments: None; XX # Revision 1.6 2019/11/22 //