AC   PRU01134;
DC   Domain;
TR   PROSITE; PS51144; ALPHA_CA_2; 1; level=0
XX
Names: Alpha-carbonic anhydrase domain
Function: Fill in
XX
case <FTGroup:1> and <FTGroup:2>
DE   + AltName: Full=Carbonic anhydrase;
DE              EC=4.2.1.1;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + hydrogencarbonate = CO2 + H2O; Xref=Rhea:RHEA:10748,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526,
CC         ChEBI:CHEBI:17544; EC=4.2.1.1;
end case
XX
case <FTGroup:2>
DR   PROSITE; PS00162; ALPHA_CA_1; 1; trigger=no
end case
XX
case <FTGroup:1> and <FTGroup:2>
GO   GO:0004089; F:carbonate dehydratase activity
end case
case <FTGroup:2> or <FTGroup:3>
GO   GO:0046872; F:metal ion binding
GO   GO:0008270; F:zinc ion binding
XX
KW   Metal-binding
KW   Zinc
end case
XX
FT   From: PS51144
FT   DOMAIN          from..to
FT                   /note="Alpha-carbonic anhydrase #"
FT   ACT_SITE        64
FT                   /note="Proton acceptor"
FT   Group: 1; Condition: H
FT   BINDING         64
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 3; Condition: H
FT   BINDING         67
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 3; Condition: H
FT   BINDING         93
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT                   /ligand_note="catalytic"
FT   Group: 2; Condition: H
FT   BINDING         95
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT                   /ligand_note="catalytic"
FT   Group: 2; Condition: H
FT   BINDING         118
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT                   /ligand_note="catalytic"
FT   Group: 2; Condition: H
FT   BINDING         201
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 3; Condition: H
XX
Chop: Nter=0; Cter=0;
Size: 15-523;
Related: None;
Repeats: 1-2;
Topology: Undefined;
Example: P22748;
Scope:
 Eukaryota
 Viruses; Orthopoxvirus
 Bacteria
Comments: None;
XX
# Revision 1.7 2022/11/19
//