AC PRU01153; DC Domain; TR PROSITE; PS51810; ZF_CCHC_FOG; 1; level=0 XX Names: Zinc finger CCHC FOG-type Function: Transcriptional cofactors of the Friend of GATA (FOG) family contain either eight or nine ZnFs that are related to the classical CCHH ZnFs (which have a conserved C-X(2,5)-C-X(12)-H-X(2,5)-H sequence). Several of the fingers in each FOG protein, however, have an altered consensus sequence in which the final zinc binding histidine is replaced with a cysteine. Interestingly, it is only these variant CCHC ZbFs that mediate interactions with GATA N-terminal zinc fingers (NFs). XX CC -!- SIMILARITY: Belongs to the FOG (Friend of GATA) family. XX GO GO:0006351; P:DNA-templated transcription case and and and GO GO:0046872; F:metal ion binding XX KW Metal-binding KW Zinc end case KW Transcription KW Transcription regulation KW Zinc-finger XX FT From: PS51810 case and and and FT ZN_FING from..to FT /note="CCHC FOG-type #" else case and and and FT ZN_FING from..to FT /note="CCHC FOG-type #; atypical" else FT ZN_FING from..to FT /note="CCHC FOG-type #; degenerate" end case FT BINDING 9 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: [CH] FT BINDING 12 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: [CH] FT BINDING 25 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: [CH] FT BINDING 30 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: [CH] XX Chop: Nter=0; Cter=0; Size: 24-44; Related: None; Repeats: 2-5; Topology: Undefined; Example: Q9VPQ6; Scope: Eukaryota; Metazoa Comments: None; XX # Revision 1.10 2022/11/19 //