AC   PRU01161;
DC   Domain;
TR   PROSITE; PS51635; PNPLA; 1; level=0
XX
Names: Patatin-like phospholipase (PNPLA) domain
Function: PNPLA domain containing proteins display lipase and transacylase
 properties and appear to have major roles in the regulation of lipid
 metabolism. The PNPLA domain has a Ser-Asp catalytic dyad.
XX
XX
case <FTGroup:1>
GO   GO:0016787; F:hydrolase activity
GO   GO:0016042; P:lipid catabolic process
XX
KW   Hydrolase
KW   Lipid degradation
KW   Lipid metabolism
end case
XX
FT   From: PS51635
FT   DOMAIN          from..to
FT                   /note="PNPLA #"
FT   MOTIF           5..10
FT                   /note="GXGXXG #"
FT   Condition: G-x-G-x-x-G
FT   MOTIF           35..39
FT                   /note="GXSXG #"
FT   Condition: G-x-S-x-G
FT   MOTIF           168..170
FT                   /note="DGA/G #"
FT   Condition: D-G-[AG]
FT   ACT_SITE        37
FT                   /note="Nucleophile"
FT   Group: 1; Condition: S
FT   ACT_SITE        168
FT                   /note="Proton acceptor"
FT   Group: 1; Condition: D
XX
Chop: Nter=0; Cter=0;
Size: 188-208;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q8LPW4;
Scope:
 Eukaryota
 Bacteria
 Viruses
Comments: None;
XX
# Revision 1.5 2019/11/22
//