AC   PRU01208;
DC   Domain;
TR   PROSITE; PS51861; OXYTX_ICK; 1; level=0
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Names: Oxytoxin-type inhibitor cystine knot (ICK) domain
Function: Oxytoxins are disulphide-rich polypeptides that contain five
 disulfide bridges and block L-, N- and P/Q-type voltage-sensitive calcium ion
 channels (VSCCs) .
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CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- DOMAIN: The presence of a 'disulfide through disulfide knot'
CC       structurally defines this protein as a knottin.
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GO   GO:0005576; C:extracellular region
GO   GO:0090729; F:toxin activity
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case <FTTag:disulf>
KW   Disulfide bond
end case
KW   Knottin
KW   Secreted
KW   Toxin
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FT   From: PS51861
FT   DOMAIN          from..to
FT                   /note="Oxytoxin-type inhibitor cystine knot (ICK) #"
FT   DISULFID        4..18
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        11..23
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        15..50
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        17..39
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        25..37
FT   Tag: disulf; Condition: C-x*-C
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Chop: Nter=0; Cter=0;
Size: 50-70;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P86716;
Scope:
 Eukaryota; Oxyopes
Comments: None;
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# Revision 1.2 2019/11/22
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