AC   PRU01210;
DC   Domain;
TR   PROSITE; PS51863; LCN_CSAB; 1; level=0
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Names: LCN-type cysteine-stabilized alpha/beta (CS-alpha/beta) domain
Function: Most long-chain neurotoxins (LCNs) are composed of 60-70 residues
 and are cross-linked by four disulphide bridges. The long chain or voltage-
 gated sodium channels scorpion neurotoxins (NaScTxs) can be classified either
 as alpha-toxins, which slow down Na(+) channel inactivation, or beta-toxins,
 which affect the channel activation process.
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CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
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GO   GO:0090729; F:toxin activity
GO   GO:0005576; C:extracellular region
GO   GO:0008200; F:ion channel inhibitor activity
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KW   Secreted
KW   Toxin
KW   Neurotoxin
case <FTTag:disulf>
KW   Disulfide bond
end case
KW   Ion channel impairing toxin
KW   Voltage-gated sodium channel impairing toxin
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FT   From: PS51863
FT   DOMAIN          from..to
FT                   /note="LCN-type CS-alpha/beta #"
FT   DISULFID        11..62
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        15..37
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        23..43
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        27..45
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        38..62
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        56..62
FT   Tag: disulf; Condition: C-x*-C
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Chop: Nter=0; Cter=0;
Size: 50-75;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P54135;
Scope:
 Eukaryota; Scorpiones
Comments: None;
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# Revision 1.2 2019/11/22
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