AC   PRU01257;
DC   Domain;
TR   PROSITE; PS51909; LYSOZYME_I; 1; level=0
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Names: Invertebrate (I)-type lysozyme domain
Function: I-type lysozymes have been identified in phylogenetically diverse
 organisms, including mollusca, nematoda, annelida, arthropoda and
 echinodermata. I-type lysozymes play an important role in immunity and
 digestion in invertebrates and are usually regarded as the first barrier
 against pathogens. I-type lysozymes exert multiple activities, such as
 muramidase, isopeptidase, chitinase, and non-enzymatic antibacterial
 activities.
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case <FTGroup:1>
DE   + RecName: EC=3.2.1.17;
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CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic
CC         acid and N-acetyl-D-glucosamine residues in a peptidoglycan and
CC         between N-acetyl-D-glucosamine residues in chitodextrins.;
CC         EC=3.2.1.17;
end case
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 22 family. Type-I
CC       lysozyme subfamily.
case <FTGroup:1>
GO   GO:0003824; F:catalytic activity
GO   GO:0019835; P:cytolysis
GO   GO:0042742; P:defense response to bacterium
GO   GO:0016798; F:hydrolase activity, acting on glycosyl bonds
GO   GO:0008152; P:metabolic process
GO   GO:0016787; F:hydrolase activity
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KW   Antimicrobial
KW   Bacteriolytic enzyme
KW   Glycosidase
KW   Hydrolase
KW   Antibiotic
end case
case <FTTag:disulf>
KW   Disulfide bond
end case
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FT   From: PS51909
FT   DOMAIN          from..to
FT                   /note="I-type lysozyme #"
FT   ACT_SITE        16
FT                   /note="Proton donor"
FT   Group: 1; Condition: E
FT   ACT_SITE        26
FT                   /note="Nucleophile"
FT   Group: 1; Condition: D
FT   DISULFID        8..91
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        11..123
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        13..19
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        23..32
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        45..73
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        63..69
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        87..105
FT   Tag: disulf; Condition: C-x*-C
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Chop: Nter=0; Cter=0;
Size: 110-130;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q8IU26;
Scope:
 Eukaryota; Metazoa
Comments: None;
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# Revision 1.2 2019/11/22
//