AC   PRU01285;
DC   Domain;
TR   PROSITE; PS51936; POU_4; 1; level=0
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Names: POU-specific (POUs) atypical domain
Function: HNF1alpha (MODY3 gene product, the most commonly mutated MODY
 protein) and HNF1beta (hepatocyte nuclear factor 1beta; also known as vHNF1
 or TCF2) (MODY5 gene product) are atypical members of the POU transcription
 factors. Their atypical POUs domains have at least one additional alpha-helix
 at the N-terminus, and the second helix and adjacent loop of their POUh
 domains are much longer, creating a more extensive interface between the POUs
 and POUh domains.
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GO   GO:0045893; P:positive regulation of DNA-templated transcription
GO   GO:0005634; C:nucleus
GO   GO:0006357; P:regulation of transcription by RNA polymerase II
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KW   DNA-binding
KW   Nucleus
KW   Transcription
KW   Transcription regulation
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FT   From: PS51936
FT   DOMAIN          from..to
FT                   /note="POU-specific atypical #"
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Chop: Nter=0; Cter=0;
Size: 90-100;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P27889;
Scope:
 Eukaryota; Metazoa
Comments: None;
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# Revision 1.2 2022/06/27
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