AC PRU01286; DC Domain; TR PROSITE; PS51937; HNF_P1; 1; level=0 XX Names: HNF-1 dimerization (HNF-p1) domain Function: The homeodomain proteins hepatocyte nuclear factor (HNF)-1alpha and HNF-1beta comprise a functionnally important family in which dimerization is essential for DNA binding. HNF-1alpha and HNF-1beta regulate tissue-specific genes in liver, kidney, intestine, and pancreas. These proteins form homo- and heterodimers through an autonomously folded domain encompassing the 32 N- terminal amino acids (HNF-p1). The dimerization domain also binds the transcriptional coactivator DCoH, which stimulates HNF-1alpha activity. XX FT From: PS51937 FT DOMAIN from..to FT /note="HNF-p1 #" XX Chop: Nter=0; Cter=0; Size: 30-35; Related: None; Repeats: 1; Topology: Undefined; Example: P27889; Scope: Eukaryota; Metazoa Comments: None; XX # Revision 1.1 2020/08/24 //