AC   PRU01298;
DC   Domain;
TR   PROSITE; PS51953; NIV_EXON; 1; level=0
XX
Names: Nidovirus 3'-5' exoribonuclease (ExoN) domain
Function: The nidovirus 3'-5' exoribonuclease (ExoN) domain may enhance the
 fidelity of RNA synthesis by correcting nucleotide incorporation errors made
 by the RNA-dependent RNA polymerase.
XX
case <FTGroup:1>
GO   GO:0004527; F:exonuclease activity
end case
XX
case <FTGroup:2> or <FTGroup:3>
GO   GO:0008270; F:zinc ion binding
GO   GO:0046872; F:metal ion binding
XX
KW   Zinc
KW   Metal-binding
KW   Zinc-finger
end case
case <FTGroup:1>
KW   Exonuclease
KW   Nuclease
end case
XX
FT   From: PS51953
FT   DOMAIN          from..to
FT                   /note="ExoN #"
FT   ACT_SITE        19
FT   Group: 1; Condition: D
FT   ACT_SITE        21
FT   Group: 1; Condition: E
FT   ACT_SITE        120
FT   Group: 1; Condition: [ED]
FT   ACT_SITE        198
FT   Group: 1; Condition: H
FT   ACT_SITE        203
FT   Group: 1; Condition: D
FT   BINDING         136
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 2; Condition: C
FT   BINDING         139
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 2; Condition: C
FT   BINDING         155
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 2; Condition: C
FT   BINDING         158
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 2; Condition: H
FT   BINDING         186
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 3; Condition: H
FT   BINDING         190
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 3; Condition: C
FT   BINDING         194
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 3; Condition: H
FT   BINDING         209
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 3; Condition: C
XX
Chop: Nter=0; Cter=0;
Size: 230-265;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P0C6Y1;
Scope:
 Viruses; Nidovirales
Comments: None;
XX
# Revision 1.4 2022/11/19
//