AC   PRU01299;
DC   Domain;
TR   PROSITE; PS51954; COV_N7_MTASE; 1; level=0
XX
Names: The Coronavirus (CoV) guanine-N7-methyltransferase (N7-MTase) domain
Function: The S-adenosyl methionine (SAM)-dependent guanine-N7-
 methyltransferase (N7-MTase) domain methylates the 5' guanine of the Gppp-RNA
 at the N7 position for mRNA capping.
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CC   -!- SIMILARITY: Belongs to the coronaviruses polyprotein 1ab family.
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GO   GO:0032259; P:methylation
GO   GO:0008168; F:methyltransferase activity
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KW   Methyltransferase
KW   Transferase
case <FTGroup:1>
KW   Metal-binding
KW   Zinc
KW   Zinc-finger
end case
FT   From: PS51954
FT   DOMAIN          from..to
FT                   /note="N7-MTase #"
FT   BINDING         36..42
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: D-x-G-x-P-x-[GA]
FT   REGION          116..130
FT                   /note="GpppA-binding"
FT   BINDING         154
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: C
FT   BINDING         174
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: C
FT   BINDING         185
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: C
FT   BINDING         188
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: H
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Chop: Nter=0; Cter=0;
Size: 220-235;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P0C6X7;
Scope:
 Viruses; Orthocoronavirinae
Comments: None;
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# Revision 1.6 2022/11/19
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