AC PRU01300; DC Domain; TR PROSITE; PS51955; NIV_2_O_MTASE; 1; level=0 XX Names: Nidovirus 2'-O-methyltransferase (2'-O-MTase) domain Function: The 3'-terminal domain of the most conserved ORF1b in three of the four families of the order Nidovirales (except for the family Arteriviridae) encodes a 2'-O-methyltransferase (2'-O-MTase), known as non structural protein (Nsp) 16 in the family Coronaviridae and implicated in methylation of the 5' cap structure of nidoviral mRNAs. XX case GO GO:0032259; P:methylation GO GO:0008168; F:methyltransferase activity XX KW Transferase KW Methyltransferase end case FT From: PS51955 FT DOMAIN from..to FT /note="Nidovirus-type SAM-dependent 2'-O-MTase #" FT ACT_SITE 45 FT Group: 1; Condition: K FT ACT_SITE 125 FT Group: 1; Condition: D FT ACT_SITE 155 FT Group: 1; Condition: K FT ACT_SITE 188 FT Group: 1; Condition: E XX Chop: Nter=0; Cter=0; Size: 255-305; Related: None; Repeats: 1; Topology: Undefined; Example: P18457; Scope: Viruses; Nidovirales Comments: None; XX # Revision 1.1 2021/01/20 //