AC PRU01303; DC Domain; TR PROSITE; PS51958; NENDOU; 1; level=0 XX Names: Nidoviral uridylate-specific endoribonuclease (NendoU) domain Function: Among the Nsps found in Nidovirales, nonstructural protein 15 (nsp15) from coronaviruses and Nsp11 from arteriviruses contain in their C- terminal region a conserved endoribonuclease domain called nidoviral uridylate-specific endoribonuclease (NendoU) with cleavage specificity for single- and double-stranded RNA 5' of uridine nucleotides to produce a 2'-3'- cyclic phosphate end product. XX XX case GO GO:0004519; F:endonuclease activity XX KW Hydrolase KW Endonuclease KW Nuclease end case XX FT From: PS51958 FT DOMAIN from..to FT /note="NendoU #" FT ACT_SITE 31 FT Group: 1; Condition: H FT ACT_SITE 46 FT Group: 1; Condition: H FT ACT_SITE 86 FT Group: 1; Condition: K XX Chop: Nter=0; Cter=0; Size: 120-150; Related: None; Repeats: 1; Topology: Undefined; Example: P0C6X9; Scope: Viruses; Nidovirales Comments: None; XX # Revision 1.2 2021/01/27 //