AC   PRU01307;
DC   Domain;
TR   PROSITE; PS51962; COV_NSP1; 1; level=0
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Names: Coronavirus (CoV) Nsp1 globular domain
Function: Nsp1 is a characteristic feature of AlphaCoVs and BetaCoVs, which
 exhibits both functional conservation and mechanistic diversity in inhibiting
 host gene expression and antiviral responses. Although the sequence
 homologies among CoV Nsp1 proteins are low, the core structures share a
 relatively conserved domain.
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CC   -!- SIMILARITY: Belongs to the coronaviruses polyprotein 1ab family.
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KW   Inhibition of host innate immune response by virus
KW   Viral immunoevasion
KW   Eukaryotic host translation shutoff by virus
KW   Host mRNA suppression by virus
KW   Inhibition of host interferon signaling pathway by virus
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FT   From: PS51962
FT   DOMAIN          from..to
FT                   /note="CoV Nsp1 globular #"
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Chop: Nter=0; Cter=0;
Size: 100-150;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P0C6U5;
Scope:
 Viruses; Orthocoronavirinae
Comments: None;
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# Revision 1.1 2021/03/02
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