AC PRU01334; DC Domain; TR PROSITE; PS51990; COV_NSP2_M; 1; level=0 XX Names: Coronavirus (CoV) Nsp2 middle domain Function: Nsp2 has been implicated in processes ranging from translation repression to endosomal transport, ribosome biogenesis, and actin filament binding. Nsp2 in SARS-CoV-2 and other coronaviruses have been observed to localize to endosomes and replication-transcription complexes (RTC). Nsp2 may be involved in binding nucleic acids and regulating intracellular signaling pathways. It contains an N-terminal, a middle and a C-terminal domain. XX CC -!- SIMILARITY: Belongs to the coronaviruses polyprotein 1ab family. XX FT From: PS51990 FT DOMAIN from..to FT /note="CoV Nsp2 middle #" XX Chop: Nter=0; Cter=0; Size: 180-400; Related: None; Repeats: 1; Topology: Undefined; Example: P0C6W5; Scope: Viruses; Orthocoronavirinae Comments: None; XX # Revision 1.1 2021/12/09 //