AC PRU01336; DC Domain; TR PROSITE; PS51992; COV_NSP3_Y; 1; level=0 XX Names: Coronavirus (CoV) Nsp3 Y domain Function: The Y domains including Y1 and CoV-Y may form higher-order oligomeric complexes and play a role in pore formation in double-membrane vesicles (DMVs) that serve as the central hubs for viral RNA replication. Specific membrane binding might be a conserved activity of the Y domain. XX CC -!- SIMILARITY: Belongs to the coronaviruses polyprotein 1ab family. XX case or GO GO:0008270; F:zinc ion binding XX KW Metal-binding KW Zinc KW Zinc-finger XX end case FT From: PS51992 FT DOMAIN from..to FT /note="CoV Nsp3 Y #" FT REGION 92..to FT /note="CoV-Y #" FT REGION from..91 FT /note="Y1 #" FT REGION 92..186 FT /note="Y2 #" FT REGION 187..268 FT /note="Y3 #" FT REGION 269..to FT /note="Y4 #" FT REGION 5..18 FT /note="ZF1 #" FT Group: 1 FT BINDING 5 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: H FT BINDING 10 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: C FT BINDING 15 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: C FT BINDING 18 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: C FT REGION 51..61 FT /note="ZF2 #" FT Group: 2 FT BINDING 51 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#2" FT Group: 2; Condition: C FT BINDING 54 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#2" FT Group: 2; Condition: H FT BINDING 58 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#2" FT Group: 2; Condition: C FT BINDING 61 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#2" FT Group: 2; Condition: C XX Chop: Nter=0; Cter=0; Size: 340-374; Related: None; Repeats: 1; Topology: Undefined; Example: P0DTD1; Scope: Viruses; Orthocoronavirinae Comments: None; XX # Revision 1.2 2023/04/06 //