AC PRU01344; DC Domain; TR PROSITE; PS52000; COV_NSP12_IF; 1; level=0 XX Names: Coronavirus Nsp12 Interface domain Function: The coronavirus Nsp12 subunit contains an N-terminal NiRAN domain, an interface domain, composed of three helices and five beta strands, and a C-terminal polymerase domain, which resembles a right hand, comprising the fingers, palm and thumb subdomains. XX DE AltName: Full=ORF1ab polyprotein; XX CC -!- SIMILARITY: Belongs to the coronaviruses polyprotein 1ab family. XX case GO GO:0008270; F:zinc ion binding XX KW Metal-binding KW Zinc end case XX FT From: PS52000 FT DOMAIN from..to FT /note="Nsp12 Interface #" FT BINDING 30 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: [HC] FT BINDING 36 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: [CH] FT BINDING 41 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: [CH] FT BINDING 45 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="#1" FT Group: 1; Condition: [CH] XX Chop: Nter=0; Cter=0; Size: 90-110; Related: None; Repeats: 1; Topology: Undefined; Example: P0C6X6; Scope: Viruses; Orthocoronavirinae Comments: None; XX # Revision 1.2 2022/11/19 //