AC   PRU01356;
DC   Domain;
TR   PROSITE; PS52012; CFEM; 1; level=0
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Names: CFEM) domain
Function: Common in Fungal Extracellular Membrane (CFEM) proteins,
 characterized by a distinctive pattern of eight cysteine residues of
 conserved interspacing, are widespread among fungi. The CFEM domain adopts a
 helical-basket fold that consists of six alpha-helices, and is uniquely
 stabilized by four disulfide bonds formed by its eight signature cysteines.
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GO   GO:0005576; C:extracellular region
case <FTTag:heme>
GO   GO:0046872; F:metal ion binding
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KW   Heme
KW   Iron
KW   Metal-binding
end case
case <FTTag:disulf>
KW   Disulfide bond
end case
FT   From: PS52012
FT   DOMAIN          from..to
FT                   /note="CFEM #"
FT   DISULFID        29..69
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        33..64
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        43..50
FT   Tag: disulf; Condition: C-x*-C
FT   DISULFID        52..85
FT   Tag: disulf; Condition: C-x*-C
FT   BINDING         47
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT   Tag: heme; Condition: D
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Chop: Nter=0; Cter=0;
Size: 107-119;
Related: None;
Repeats: 1-4;
Topology: Undefined;
Example: Q4WMA6;
Scope:
 Eukaryota; Ascomycota
Comments: None;
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# Revision 1.1 2022/11/10
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