AC   PRU01379;
DC   Domain;
TR   PROSITE; PS52035; PEPTIDASE_M14; 1; level=0
XX
Names: Peptidase family M14 domain
Function: M14 metallocarboxypeptidases are a diverse and important class of
 peptidases that catalyze the removal of the C-terminal residue from
 polypeptides by means of a coordinated Zn(2+) cofactor.
XX
case <FTGroup:1>
CC   -!- COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
end case
CC   -!- SIMILARITY: Belongs to the peptidase M14 family.
XX
case <FTGroup:1>
GO   GO:0008270; F:zinc ion binding
end case
case <FTTag:act_site> and <FTGroup:1>
GO   GO:0004181; F:metallocarboxypeptidase activity
GO   GO:0006508; P:proteolysis
XX
KW   Carboxypeptidase
KW   Hydrolase
KW   Metalloprotease
KW   Protease
end case
case <FTGroup:1>
KW   Metal-binding
KW   Zinc
end case
XX
FT   From: PS52035
FT   DOMAIN          from..to
FT                   /note="Peptidase M14 #"
FT   ACT_SITE        256
FT                   /note="Proton donor/acceptor"
FT   Tag: act_site; Condition: E
FT   BINDING         62
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: H
FT   BINDING         65
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: E
FT   BINDING         182
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: H
XX
Chop: Nter=0; Cter=0;
Size: 234-454;
Related: None;
Repeats: 1-3;
Topology: Undefined;
Example: Q09M02;
Scope:
 Eukaryota
 Bacteria
Comments: None;
XX
# Revision 1.2 2023/08/29
//