AC   PRU01388;
DC   Domain;
TR   PROSITE; PS52043; UBR4_E3; 1; level=0
XX
Names: UBR4 E3 catalytic module
Function: The UBR4 E3 catalytic module that carries out ubiquitin (Ub)
 transfer consists of a 'hemiRING' zinc finger, a helical-rich UBR zinc-finger
 interacting (UZI) subdomain, and an N-terminal region that can serve as an
 affinity factor for the E2 conjugating enzyme (E2).
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CC   -!- SIMILARITY: Belongs to the UBR4 family.
XX
case <Feature:PS52043:133=[CH]> and <Feature:PS52043:136=[CH]> and <Feature:PS52043:183=[CH]> and <Feature:PS52043:186=[CH]>
GO   GO:0046872; F:metal ion binding
GO   GO:0008270; F:zinc ion binding
GO   GO:0006511; P:ubiquitin-dependent protein catabolic process
GO   GO:0004842; F:ubiquitin-protein transferase activity
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KW   Metal-binding
KW   Zinc
end case
KW   Zinc-finger
XX
FT   From: PS52043
FT   REGION          from..to
FT                   /note="UBR4 E3 catalytic module #"
case <Feature:PS52043:133=[C]> and <Feature:PS52043:136=[C]> and <Feature:PS52043:183=[H]> and <Feature:PS52043:186=[C]>
FT   ZN_FING         130..249
FT                   /note="HemiRING-type #"
else case <Feature:PS52043:133=[CH]> and <Feature:PS52043:136=[CH]> and <Feature:PS52043:183=[CH]> and <Feature:PS52043:186=[CH]>
FT   ZN_FING         130..249
FT                   /note="HemiRING-type #; atypical"
else
FT   ZN_FING         130..249
FT                   /note="HemiRING-type #; degenerate"
end case
FT   BINDING         133
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         136
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         183
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         186
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   DOMAIN          252..to
FT                   /note="UZI #"
XX
Chop: Nter=0; Cter=0;
Size: 466-531;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q9VLT5;
Scope:
 Eukaryota
Comments: None;
XX
# Revision 1.1 2024/04/12
//