AC   PRU01406;
DC   Domain;
TR   PROSITE; PS52061; DAHPS_I; 1; level=0
XX
Names: DAHPS class-I core TIM-barrel domain
Function: Although there is no significant sequence similarity between the
 class-II DAHPSs and the class-I DAHPSs and KDOPSs, they share a
 characteristic (beta/alpha)8 TIM-barrel fold in which the eight parallel
 beta-strands are each followed by alpha-helices, and similar active site
 architecture.
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CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
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GO   GO:0005737; C:cytoplasm
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KW   Cytoplasm
case <FTGroup:1> and (<FTGroup:2> or <FTGroup:3>)
KW   Transferase
else case <FTGroup:1>
KW   Metal-binding
end case
FT   From: PS52061
FT   DOMAIN          from..to
FT                   /note="DAHPS class-I TIM-barrel #"
FT   BINDING         11
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: C
FT   BINDING         36
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Group:3; Condition: [KR]
FT   BINDING         41
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Group:3; Condition: K
case not <FTGroup:2>
FT   BINDING         94
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 3; Condition: Q
end case
FT   BINDING         97
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Condition: A
FT   BINDING         98
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Condition: R
FT   BINDING         119
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Group:3; Condition: K
FT   BINDING         149
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Group:3; Condition: R
FT   BINDING         184
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Condition: H
FT   BINDING         184
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: H
FT   BINDING         210
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: E
FT   BINDING         221
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: D
XX
Chop: Nter=0; Cter=0;
Size: 124-312;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: A1US93;
Scope:
 Bacteria
 Eukaryota
Comments: None;
XX
# Version: 2
# Last updated date: 2025-04-08
# Created date: 2025-04-08
//