AC   PRU01407;
DC   Domain;
TR   PROSITE; PS52062; DAHPS_II; 1; level=0
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Names: DAHPS class-II core TIM-barrel domain
Function: Although there is no significant sequence similarity between the
 class-II DAHPSs and the class-I DAHPSs and KDOPSs, they share a
 characteristic (beta/alpha)8 TIM-barrel fold in which the eight parallel
 beta-strands are each followed by alpha-helices, and similar active site
 architecture.
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CC   -!- SIMILARITY: Belongs to the class-II DAHP synthase family.
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case <FTGroup:1> and <FTGroup:2>
KW   Transferase
KW   Metal-binding
end case
FT   From: PS52062
FT   DOMAIN          from..to
FT                   /note="DAHPS class-II TIM-barrel #"
FT   BINDING         11
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: C
FT   BINDING         50
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Condition: R
FT   BINDING         208
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Condition: [ED]
FT   BINDING         209
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Condition: R
FT   BINDING         231
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Condition: K
FT   BINDING         262
FT                   /ligand="phosphoenolpyruvate"
FT                   /ligand_id="ChEBI:CHEBI:58702"
FT   Group: 2; Condition: R
FT   BINDING         294
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: H
FT   BINDING         336
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: E
FT   BINDING         366
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: D
XX
Chop: Nter=0; Cter=0;
Size: 18-415;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P21357;
Scope:
 Eukaryota
 Bacteria
Comments: None;
XX
# Version: 3
# Last updated date: 2025-04-07
# Created date: 2025-04-04
//