AC   PRU01416;
DC   Domain;
TR   PROSITE; PS52071; GPN_LOOP_GTPASE; 1; level=0
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Names: GPN-loop GTPase domain
Function: GPN-loop GTPases are assembly chaperones for RNA polymerase II (Pol
 II) and other protein complexes. This family of conserved GTPases has been
 named GPN-loop GTPases due to the presence of a conserved Gly-Pro-Asn motif
 inserted into the GTPase core-fold. GPN-loop GTPases form homo- and
 heterodimers.
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CC   -!- SIMILARITY: Belongs to the GPN-loop GTPase family.
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case <FTGroup:1>
GO   GO:0005525; F:GTP binding
GO   GO:0003924; F:GTPase activity
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KW   GTP-binding
KW   Hydrolase
KW   Nucleotide-binding
end case
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FT   From: PS52071
FT   DOMAIN          from..to
FT                   /note="GPN-loop core GTPase #"
FT   MOTIF           9..16
FT                   /note="G1 #"
FT   Group: 1; Condition: G-x(2)-[GS]-x-G-K-[TS]
case <Feature:PS52071:36-39=[VIL]-N-[LM]-D>
FT   MOTIF           36..39
FT                   /note="G2 #"
FT   Group: 1
else case <Feature:PS52071:35-39=[VIL]-x(0,1)-N-[LM]-D>
FT   MOTIF           35..39
FT                   /note="G2 #"
FT   Group: 1;
end case
FT   MOTIF           69..71
FT                   /note="Gly-Pro-Asn (GPN)-loop; involved in dimer interface"
FT   Condition: G-P-N
FT   MOTIF           103..107
FT                   /note="G3 #"
FT   Group: 1; Condition: D-x-P-G-Q
FT   MOTIF           170..173
FT                   /note="G4 #"
FT   Group: 1; Condition: [NST]-K-x-D
FT   MOTIF           228..230
FT                   /note="G5 #"
FT   Group: 1;
XX
Chop: Nter=0; Cter=0;
Size: 247-284;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q4V7Z0;
Scope:
 Eukaryota
 Archaea; Pyrococcus
Comments: None;
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# Version: 2
# Last updated date: 2025-06-30
# Created date: 2025-06-30
//