AC PRU01420; DC Domain; TR PROSITE; PS52075; IFN_I; 1; level=0 XX Names: Interferon (IFN) type-I family Function: Type I IFNs are widespread in vertebrates from fish to mammals and include the IFN-alpha family of subtypes, a single IFN-beta and several poorly defined single gene products (IFN-epsilon, IFN-tau, IFN-kappa, IFN- omega, IFN-delta and IFN-zeta. Type I IFNs have diverse effects on innate and adaptive immune cells during infection with viruses, bacteria, parasites and fungi, directly and/or indirectly through the induction of other mediators. Type I IFNs are important for host defence against viruses XX CC -!- SUBCELLULAR LOCATION: Secreted. CC -!- SIMILARITY: Belongs to the type-I (or alpha/beta) interferon family. XX DR PROSITE; PS00252; INTERFERON_A_B_D; 0-1; trigger=no DR PROSITE; PS00001; ASN_GLYCOSYLATION; 0-1; trigger=yes XX GO GO:0005125; F:cytokine activity GO GO:0005615; C:extracellular space GO GO:0051607; P:defense response to virus XX KW Antiviral defense KW Cytokine KW Secreted case KW Disulfide bond end case FT From: PS52075 FT DISULFID 1..99 FT Tag: disulf; Condition: C-x*-C FT DISULFID 29..139 FT Tag: disulf; Condition: C-x*-C FT DISULFID 36..126 FT Tag: disulf; Condition: C-x*-C FT DISULFID 64..86 FT Tag: disulf; Condition: C-x*-C XX Chop: Nter=0; Cter=0; Size: 152-176; Related: None; Repeats: 1; Topology: Undefined; Example: P01574; Scope: Eukaryota; Euteleostomi Comments: None; XX # Log: //