AC   PRU01422;
DC   Domain;
TR   PROSITE; PS52077; IFN_III; 1; level=0
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Names: Interferon (IFN) type-III family
Function: Type III IFNs, commonly known as interferon lambda (IFNL or IFN-
 lambda), have been reported in mammals, birds, reptiles, amphibians, and
 cartilaginous fish. IFN-IIIs include IFN-lambda1-3 (also known as interleukin
 [IL]-29, IL-28A, and IL-28B) and IFN-lambda4 (only IFN-lambda2 and IFN-
 lambda3 exist in mice). They play a crucial role as gatekeepers, particularly
 in safeguarding mucosal epithelial cells.
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CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the type-III (or lambda) interferon family.
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DR   PROSITE; PS00001; ASN_GLYCOSYLATION; 0-1; trigger=yes
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GO   GO:0005125; F:cytokine activity
GO   GO:0050778; P:positive regulation of immune response
GO   GO:0051607; P:defense response to virus
GO   GO:0005615; C:extracellular space
GO   GO:0045087; P:innate immune response
GO   GO:0005102; F:signaling receptor binding
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KW   Antiviral defense
KW   Cytokine
KW   Secreted
case <FTGroup:1> or <FTGroup:2> or <FTGroup:3>
KW   Disulfide bond
end case
FT   From: PS52077
case (<Feature:PS52077:3-102=C-x*-C> and <Feature:PS52077:35-135=C-x*-C> and<Feature:PS52077:48-161=C-x*-C>)
FT   DISULFID        3..102
FT   Group: 1;
FT   DISULFID        35..135
FT   Group: 1;
FT   DISULFID        48..161
FT   Group: 1;
else case (<Feature:PS52077:3-102=C-x*-C> and <Feature:PS52077:37-135=C-x*-C> and<Feature:PS52077:154-161=C-x*-C>)
FT   DISULFID        3..102
FT   Group: 2
FT   DISULFID        37..135
FT   Group: 2;
FT   DISULFID        154..161
FT   Group: 2;
else case (<Feature:PS52077:37-135=C-x*-C>)
FT   DISULFID        37..135
FT   Group: 3; Condition: C-x*-C
end case
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Chop: Nter=0; Cter=0;
Size: 155-162;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: Q8IU54;
Scope:
 Eukaryota; Euteleostomi
Comments: None;
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# Log: 
//