AC PRU01423; DC Domain; TR PROSITE; PS52078; IFN_IV; 1; level=0 XX Names: Interferon (IFN) type-IV family Function: IFN-upsilon (IFNU), the type IV IFN, is found in jawed vertebrates ranging from cartilaginous fish to primitive mammals. It differs from type I, II, and III IFNs in consideration of sequence feature, gene locus, phylogeny, and receptor complex. IFN-upsilon proteins in vertebrates were reported to contain conserved sequence, CXXXXX(W/L) at N-terminus, being different from other known three types of IFNs. XX CC -!- SUBCELLULAR LOCATION: Secreted. CC -!- SIMILARITY: Belongs to the type-IV (or upsilon) interferon family. XX DR PROSITE; PS00001; ASN_GLYCOSYLATION; 0-1; trigger=yes XX GO GO:0005125; F:cytokine activity GO GO:0050778; P:positive regulation of immune response GO GO:0051607; P:defense response to virus GO GO:0005615; C:extracellular space GO GO:0045087; P:innate immune response GO GO:0005102; F:signaling receptor binding XX KW Antiviral defense KW Cytokine KW Secreted XX Chop: Nter=0; Cter=0; Size: 95-205; Related: None; Repeats: 1; Topology: Undefined; Example: A0A6P6J8D3; Scope: Eukaryota; Euteleostomi Comments: None; XX # Log: //