AC   PRU01453;
DC   Domain;
TR   PROSITE; PS52109; FV_L_CT; 1; level=0
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Names: Filovirus large (L) protein C-terminal (CTD) domain
Function: The filovirus L CTD, which is enriched in basic amino acids, plays a
 key role in RNA binding and in turn regulates the different MTase activities.
 It selectively contributes to the right positioning of RNA in the MTase
 catalytic site, thereby regulating the different MTase activities of the
 protein. Consequently, it participates in viral replication and escape of the
 host innate immunity.
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DE   + AltName: Full=RNA-directed RNA polymerase L;
DE            Short=Protein L;
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CC   -!- SUBCELLULAR LOCATION: Host cytoplasm. Virion.
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FT   From: PS52109
FT   DOMAIN          from..to
FT                   /note="Filovirus L C-terminal #"
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Chop: Nter=0; Cter=0;
Size: 169-170;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P35262;
Scope:
 Viruses; Filoviridae
Comments: None;
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# Version: 2
# Last updated date: 2026-06-16
# Created date: 2026-06-11
//