AC   PRU10096;
DC   Domain;
TR   PROSITE; PS00143; INSULINASE; 1; level=0
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Names: Insulinase family, zinc-binding region
Function: Undefined
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DE   + AltName: Full=Pitrilysin;
DE            EC=3.4.24.55;
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CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Preferential cleavage of 16-Tyr-|-Leu-17 and 25-Phe-|-Tyr-26
CC         bonds of oxidized insulin B chain. Also acts on other substrates of
CC         Mw less than 7 kDa such as insulin and glucagon.; EC=3.4.24.55;
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FT   From: PS00143
FT   BINDING         4
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   ACT_SITE        7
FT                   /note="Proton acceptor"
FT   BINDING         8
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
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Chop: Nter=0; Cter=0;
Size: unlimited;
Related: None;
Repeats: 1;
Topology: Undefined;
Example: P27508;
Scope:
 Eukaryota
 Bacteria
Comments: None
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# Revision 1.7 2022/11/19
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